UniProt Accession

 E9PP83_HUMAN; E9PP83 

Genbank Protein ID

 AC090719 

Genbank Nucleotide ID

  

Protein Name

 E3 ubiquitin-protein ligase TRIM68 

Protein Synonyms/Alias

  

Gene Name

 TRIM68 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
48	QEVLNRSKSWSLQQP	ubiquitination	[1, 2]
63	EPISLELKTDCRVLG	ubiquitination	[2]
76	LGLREILKTYAADVR	ubiquitination	[2]
110	HYGDTNQKLPDNPER	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 142 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA. 

Interpro

 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR006574; PRY. 

Pfam

  

SMART

 SM00589; PRY 

PROSITE

 PS50188; B302_SPRY 

PRINTS

 PR01407; BUTYPHLNCDUF.