CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016202
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetraspanin-33 
Protein Synonyms/Alias
 Tspan-33; Penumbra; hPen; Proerythroblast new membrane 
Gene Name
 TSPAN33 
Gene Synonyms/Alias
 PEN 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
152NLIDFGQKKFSCCGGubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors (By similarity). 
Sequence Annotation
 CARBOHYD 172 172 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 283 AA 
Protein Sequence
MARRPRAPAA SGEEFSFVSP LVKYLLFFFN MLFWVISMVM VAVGVYARLM KHAEAALACL 60
AVDPAILLIV VGVLMFLLTF CGCIGSLREN ICLLQTFSLC LTAVFLLQLA AGILGFVFSD 120
KARGKVSEII NNAIVHYRDD LDLQNLIDFG QKKFSCCGGI SYKDWSQNMY FNCSEDNPSR 180
ERCSVPYSCC LPTPDQAVIN TMCGQGMQAF DYLEASKVIY TNGCIDKLVN WIHSNLFLLG 240
GVALGLAIPQ LVGILLSQIL VNQIKDQIKL QLYNQQHRAD PWY 283 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR008952; Tetraspanin_EC2. 
Pfam
 PF00335; Tetraspannin 
SMART
  
PROSITE
  
PRINTS
 PR00259; TMFOUR.