CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020095
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G patch domain-containing protein 1 
Protein Synonyms/Alias
 Evolutionarily conserved G-patch domain-containing protein 
Gene Name
 GPATCH1 
Gene Synonyms/Alias
 ECGP; GPATC1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
330WTAPRQYKNQKESEKacetylation[1]
333PRQYKNQKESEKDLRacetylation[1]
337KNQKESEKDLRYVGKacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 152 198 G-patch.
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 6 6 Phosphoserine.
 MOD_RES 8 8 Phosphoserine.  
Keyword
 Acetylation; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 931 AA 
Protein Sequence
MAARDSDSEE DLVSYGTGLE PLEEGERPKK PIPLQDQTVR DEKGRYKRFH GAFSGGFSAG 60
YFNTVGSKEG WTPSTFVSSR QNRADKSVLG PEDFMDEEDL SEFGIAPKAI VTTDDFASKT 120
KDRIREKARQ LAAATAPIPG ATLLDDLITP AKLSVGFELL RKMGWKEGQG VGPRVKRRPR 180
RQKPDPGVKI YGCALPPGSS EGSEGEDDDY LPDNVTFAPK DVTPVDFTPK DNVHGLAYKG 240
LDPHQALFGT SGEHFNLFSG GSERAGDLGE IGLNKGRKLG ISGQAFGVGA LEEEDDDIYA 300
TETLSKYDTV LKDEEPGDGL YGWTAPRQYK NQKESEKDLR YVGKILDGFS LASKPLSSKK 360
IYPPPELPRD YRPVHYFRPM VAATSENSHL LQVLSESAGK ATPDPGTHSK HQLNASKRAE 420
LLGETPIQGS ATSVLEFLSQ KDKERIKEMK QATDLKAAQL KARSLAQNAQ SSRAQLSPAA 480
AAGHCSWNMA LGGGTATLKA SNFKPFAKDP EKQKRYDEFL VHMKQGQKDA LERCLDPSMT 540
EWERGRERDE FARAALLYAS SHSTLSSRFT HAKEEDDSDQ VEVPRDQEND VGDKQSAVKM 600
KMFGKLTRDT FEWHPDKLLC KRFNVPDPYP DSTLVGLPRV KRDKYSVFNF LTLPETASLP 660
TTQASSEKVS QHRGPDKSRK PSRWDTSKHE KKEDSISEFL SLARSKAEPP KQQSSPLVNK 720
EEEHAPELSA NQTVNKDVDA QAEGEGSRPS MDLFRAIFAS SSDEKSSSSE DEQGDSEDDQ 780
AGSGEANFQS SQDTDLGETS SVAHALVPAP QEPPPSFPIQ KMQIDEREEF GPRLPPVFCP 840
NARQTLEVPQ KEKHKKNKDK HKAKKEHRRK KEKKKKHRKH KHKGKQKNKK PEKSSSSESS 900
DSSDSQSDEE TADVSPQELL RRLKSLPLRR Q 931 
Gene Ontology
 GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB. 
Interpro
 IPR011666; DUF1604.
 IPR000467; G_patch_dom. 
Pfam
 PF07713; DUF1604
 PF01585; G-patch 
SMART
 SM00443; G_patch 
PROSITE
 PS50174; G_PATCH 
PRINTS