UniProt Accession

 RB33B_MOUSE; O35963; Q3TWI8 

Genbank Protein ID

 AB004665; AB004664; AK004974; AK087967; AK139821; AK159674; BC065076 

Genbank Nucleotide ID

 BAA22655.1; BAA22654.1; BAB23710.1; BAC40064.1; BAE24147.1; BAE35278.1; AAH65076.1 

Protein Name

 Ras-related protein Rab-33B 

Protein Synonyms/Alias

  

Gene Name

 Rab33b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
149	PRILVGNKCDLRSAI	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulator of autophagosome formation. 

Sequence Annotation

 NP_BIND 39 46 GTP.
 NP_BIND 88 92 GTP.
 NP_BIND 148 151 GTP.
 NP_BIND 178 180 GTP.
 MOD_RES 229 229 Cysteine methyl ester (By similarity).
 LIPID 227 227 S-geranylgeranyl cysteine (By
 LIPID 229 229 S-geranylgeranyl cysteine (By  

Keyword

 3D-structure; Autophagy; Complete proteome; Direct protein sequencing; Golgi apparatus; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 229 AA 

Protein Sequence

Gene Ontology

 GO:0005796; C:Golgi lumen; IDA:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:2000785; P:regulation of autophagic vacuole assembly; IMP:UniProtKB.
 GO:2000156; P:regulation of retrograde vesicle-mediated transport, Golgi to ER; ISS:UniProtKB.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.