CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044585
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Lethal(2) giant larvae protein homolog 2 
Protein Synonyms/Alias
  
Gene Name
 Llgl2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
852FKVFTLPKVSAKLKLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1051 AA 
Protein Sequence
MRRFLRTGHD PARERLKRDL FQFNKTVEHG FPHQPSALGY SPSLRILAIG TRSGAVKLYG 60
APGVEFMGLH KENNAVLQIH FLPGQCQLVT LLDDNSLHLW SLKVKGGVSE LQEEESFTLR 120
GPPGAAPSAT QVTEILPHSS GELLYLGTES GNVFVVQLPG FRTLHDRTIC SDEVLQWLPE 180
EARHRRVFEM VEALQEHPRD PNQILIGYSR GLVVIWDLQG SRALSHFLSS QQLENASWQR 240
DGCLIVTCHS DGSHCQWPVS SDTQNPEPLR SSIPYGPFPC KAITKIFWLT TRQGLPFTIF 300
QGGMPRASYG DRHCISVVHN GQQTAFDFTS RVIDFTVLSE ADPAAAFDDP YALVVLAEEE 360
LVVIDLQTPG WPPVQLPYLA SLHCSAITCS HHVSNIPLKL WERIIAAGSR QNSHFSTMEW 420
PIDGGTSLAP PPPQRDLLLT GHEDGTVRFW DASGVCLRLL YKLSTVRVFL TDTDPSENLI 480
AQGEDEWPPL RKVGSFDPYS DDPRLGIQKI FLCKYSGYLA VAGTAGQVLV LELNDEAAEH 540
AVEQVEADLL QDQEGYRWKG HERLAARPGP VCFEAGFQPF VLVQCQPPAV VTSLALHSEW 600
RLVAFGTSHG FGLFDHQQRR QVFVKCTLHP SDQLALEGPL SRVKSLKKSL RQSFRRMRRS 660
RVSSHKRRPG GPTGEVRPQA QSSHLQDHTA LPQDLNPDQA QAQAVNIKAE RTGLQNMELA 720
PVQRKIEARS AEDSFTGFVR TLYFADTYLR DSSRHCPSLW AGTNGGTVYA FSLRVPPAER 780
RTDEPVRAEQ AKEIQLMHRA PVVGILVLDG HNVPLPEPLE VAHDLSKSPD MQGSHQLLVV 840
SEEQFKVFTL PKVSAKLKLK LTALEGSRVR RVGVAHFGSC RAEDYGEHHL AVLTNLGDIQ 900
VVSMPLLKPQ VRYSCIRRED VSGIASCVFT KYGQGFYLIS PSEFERFSLS TKWLVEPRCL 960
VDSTKAKKHN RPSNGNGTGL KMTSSGHVRN SKSQSDGDEK KPGPVMEHAL LNDAWVLKEI 1020
QSTLEGDRRS YGNWHPHRVA VGCRLSNGEA E 1051 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara.
 GO:0032878; P:regulation of establishment or maintenance of cell polarity; IEA:Compara. 
Interpro
 IPR000664; Lethal2_giant.
 IPR013577; LLGL2.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF08366; LLGL
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2 
PRINTS
 PR00962; LETHAL2GIANT.