CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027438
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 S-adenosylmethionine decarboxylase-ornithine decarboxylase 
Protein Synonyms/Alias
  
Gene Name
 PF10_0322 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
559RVQYFVYKLRDVVKCacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1434 AA 
Protein Sequence
MNGIFEGIEK RVVIKLKESF FKGNRNVNSF LDIPKELWEE KLKYIGCSIV SEISEDKNER 60
RGERCRVYLL SESSLYIFDD SLFIKTCGKT RVLFFIPFVV DLLIYHMDNV GIIEKNCVYD 120
ETFIENEKFH NIAEFIKEHF LYCFFTHMNY RNKTKDGYFE QEYPHKSLED EKKFFEFFFK 180
NVQMYNTHLP MEKMHYIFFY SSDDVHMTDI ASTFKFCSEI HLFGINKYNE KNQFHDAYLN 240
NKSLNLFTRV HEDNLKLYDS SDADKEVTTH IYSTRGTYED TGMVNCVDVI YKNESTLLNR 300
NNIENIPSIE NKESNNNSRC CHNNNYSGSC HNIVSVVPSE RNNDHVHHRH YEDTLNRSNI 360
SAEDNNRNAQ LEKEKDEDVR RDDEENKVLI KMIDTNLYEC INYNKESFLY NEFYFTPCGY 420
SCNVSEKNNY FCVHYSPEDS VSYVSVEVSS NLSCDRFLDF MHKQLNFYNG KYMFMINYVF 480
CEESNNMSKM VPDDDNNNYS SGKSCVYYQD LNKKEKEEYY RLNKKLRNDL FINSKQFYEL 540
HTFTERTVGF MRVQYFVYKL RDVVKCVEKE TLLARSSSCL FMFNNIKRND VHDDYVTKSS 600
NGGVIKQLTE RDVDDMYEYA LNFCKQNKIV VVDTNTFFDA SKRKENLIKL EKVQTNEKDE 660
YEEKDEVYRR GNNELSSLDH LDSKNNLIHM YYEKNKCDII NKDDENSTIA TNNNDNNNDN 720
NNDSSSYDKS ITISRSSSCN NSHLSYSSFD NNHGNEKMKD YISVDENNNN NNNNNNNNNN 780
NNNKNNNVLL TLQRNSDDEN GKDKDNEKND VSLENNMEKN YKEEIWNYYT KNKVEVKTLE 840
KVLNENIDTS VVCINLQKIL AQYVRFKKNL PHVTPFYSVK SNNDEVVIKF LYGLNCNFDC 900
ASIGEISKVI KLLPNLSRDR IIFANTIKSI NSLIYARKEN INLCTFDNLD ELKKIYKYHP 960
KCSLILRINV DFKNYKSYMS SKYGANEYEW EEMLLYAKKH NLNIVGVSFH VGSNTKNLFD 1020
FCLAIKLCRD VFDMSSNMGF NFYIINLGGG YPEELEYDNA KKHDKIHYCT LSLQEIKKDI 1080
QKFLNEETFL KTKYGYYSFE KISLAINMSI DHYFSHMKDN LRVICEPGRY MVAASSTLAV 1140
KIIGKRRPTF QGIMLKDLKD HYDPLNFAQQ ENKKQDETKI NHNNDNNDNN DNNDNNDNNI 1200
NNNNNNQKGG QGNIMNDLII TSTNDSTNKK NDHSSSQVIQ NVSCTIRDKE GDNIKINTHT 1260
INNPNINGKE NTVDGDNINI AHKNIGNNFS SSNSKLGNIT NIKKKVVNIN DNRYNYFSYY 1320
VSDSIYGCFS GIIFDEYNRC PIYVIKNKNN PNQNFMNFNL YLANVFGQSC DGLDMINSIT 1380
YLPECYINDW LLYEYAGAYT FVSSSNFNGF KKCKKVYIFP ESKPSLKGQP NKHW 1434 
Gene Ontology
 GO:0004014; F:adenosylmethionine decarboxylase activity; IEA:InterPro.
 GO:0004586; F:ornithine decarboxylase activity; IDA:GeneDB_Pfalciparum.
 GO:0009445; P:putrescine metabolic process; ISS:GeneDB_Pfalciparum.
 GO:0008295; P:spermidine biosynthetic process; IEA:InterPro.
 GO:0006597; P:spermine biosynthetic process; IEA:InterPro. 
Interpro
 IPR009006; Ala_racemase/Decarboxylase_C.
 IPR022643; De-COase2_C.
 IPR022644; De-COase2_N.
 IPR000183; Orn/DAP/Arg_de-COase.
 IPR002433; Orn_de-COase.
 IPR001985; S-AdoMet_decarboxylase.
 IPR016067; S-AdoMet_deCO2ase_core. 
Pfam
 PF02784; Orn_Arg_deC_N
 PF00278; Orn_DAP_Arg_deC
 PF01536; SAM_decarbox 
SMART
  
PROSITE
  
PRINTS
 PR01179; ODADCRBXLASE.
 PR01182; ORNDCRBXLASE.