UniProt Accession

 Q91VB8_MOUSE; Q91VB8 

Genbank Protein ID

 AL662780; BC043020; AY016021; AY016021; EF605472; AK003077; AK005434; AK010923; AK010927; AK010933; AK010937; AK010987; AK011018; AK011023; AK011025; AK011028; AK011030; AK011055; AK011073; AK011121; AK012329; AK012348; AK012755; AK019138; AK028173; AK171893 

Genbank Nucleotide ID

 AAH43020.1; AAL32371.1; AAL32372.1; ABU54054.1; BAB22552.1; BAB24028.1; BAB27269.1; BAB27272.1; BAB27277.1; BAB27279.1; BAB27307.1; BAB27336.1; BAB27340.1; BAB27342.1; BAB27344.1; BAB27346.1; BAB27364.1; BAB27378.1; BAB27414.1; BAB28166.1; BAB28179.1; BAB28446.1; BAB31564.1; BAC25790.1; BAE42724.1 

Protein Name

 Alpha globin 1 

Protein Synonyms/Alias

 Alpha globin 2; Alpha-globin; Hemoglobin alpha, adult chain 1; Hemoglobin subunit alpha; Protein Hba-a2 

Gene Name

 Hba-a1 

Gene Synonyms/Alias

 haemaglobin alpha 1; haemaglobin alpha 2; Hba-a2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
8	MVLSGEDKSNIKAAW	acetylation	[1]
8	MVLSGEDKSNIKAAW	ubiquitination	[2]
12	GEDKSNIKAAWGKIG	ubiquitination	[2]
17	NIKAAWGKIGGHGAE	acetylation	[1]
17	NIKAAWGKIGGHGAE	ubiquitination	[2]
41	FASFPTTKTYFPHFD	ubiquitination	[2]
57	SHGSAQVKGHGKKVA	ubiquitination	[2]
62	QVKGHGKKVADALAN	ubiquitination	[2]
91	LSDLHAHKLRVDPVN	ubiquitination	[2]
140	VSTVLTSKYR*****	acetylation	[1]
140	VSTVLTSKYR*****	ubiquitination	[2]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in oxygen transport from the lung to the various peripheral tissues (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Heme; Iron; Metal-binding; Oxygen transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 142 AA 

Protein Sequence

Gene Ontology

 GO:0005833; C:hemoglobin complex; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0019825; F:oxygen binding; IEA:InterPro.
 GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. 

Interpro

 IPR000971; Globin.
 IPR009050; Globin-like.
 IPR012292; Globin_dom.
 IPR002338; Haemoglobin_a.
 IPR018331; Haemoglobin_alpha_chain.
 IPR002339; Haemoglobin_pi. 

Pfam

 PF00042; Globin 

SMART

  

PROSITE

 PS01033; GLOBIN 

PRINTS

 PR00612; ALPHAHAEM.
 PR00815; PIHAEM.