Tag | Content |
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CPLM ID | CPLM-031863 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein kinase domain-containing protein |
Protein Synonyms/Alias | Protein kinase domain-containing protein, putative |
Gene Name | TGGT1_059690, TGME49_101270 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Toxoplasma gondii |
NCBI Taxa ID | 5811 |
Lysine Modification | Position | Peptide | Type | References |
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3274 | SRGRCLGKEGEKIRT | acetylation | [1] | 3479 | LAAPFAAKPATQTAP | acetylation | [1] |
|
Reference | [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii. Jeffers V, Sullivan WJ Jr. Eukaryot Cell. 2012 Jun;11(6):735-42. [ PMID: 22544907] |
Functional Description | |
Sequence Annotation | |
Keyword | Hydrolase; Kinase; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3520 AA |
Protein Sequence | MGGGVGRAPR AGRGASVSDS EALSLPALLP PLSPLSSPSP ALGDSACFPF IGLEPLKPPA 60 GGRGSPASPV RSLSSILIVS SASAAAFVRS ASSSFASSLS SRASSSSAPV PVYIHPVSGT 120 VHPYPAQPAP PPPTHLVLAV PASASYAPPA SSSSSSFLEG LSVGFSGVSG RTSARATAQE 180 KPDASFFAAL QTSVVQLLKR SRSIRSVVLR GDGDWLEVLR EALQNHVSVS SVSLEAVTNL 240 SEKELTSGYA RLLSGLSKCT SISIRGCGLT SRGLKSLLRS LGKQSDFVEH LQEIDLAHND 300 LDDEAAAVLL SLFSSSSPRR LASLRLDANP CSLSALEPLL ALLASCDGAS SEEESGLNLL 360 SLGGLTNSAF LSTLTHLDLS HVPSLLSDDD VALLVEILFP RESLPRLQTR GGRDERGKSP 420 ACTRKPQTAK GRDRSVSAVS SVSSLLSLSL AGDGLTGGCL RALALGLLSP SCRLQHLDLS 480 RNSFGKKPSI DGDAGSDSHA PERKDKDKRR AKGRPGARKR PEEKEEEALP IEPLVDALQQ 540 GYEEAPHAPC GLRFLSLAFC ELSLEAMQQL AAALLTNGEN LVFLDLRGNL RSAEGPDGGE 600 EQRKGDRRDE LRLARCAFDT VAGMCGLQVL LLEEETKKRR QETEETEETE ETQETGRKRQ 660 KRGTRQPKGR RRDKATEEAN EEEGTVEEGE DEEDEEEDDE KHGEEGTRGV RGGRAVEIER 720 RRCGGKGGRG RRSEKSESKK RKAEMAEEDS GRSSVRTRRQ RKDDEEEEEE EEEEEEEEEE 780 EEDDEEEEED DEEDESFDEL DAMEAEQKAD ESSEDEGGED GEEKEEDEEE EEEEDETTRT 840 SLRKRGRHSG MRSEKEQESL SKATEPRQRT MESENGGKTT PRRGRPTRRT SADSSRRKKS 900 KKDESEEEEE EEDEEEEEEE EEEEEDDDDE EYEEGESVTG RKGRRRRHPQ RGRDQVVSAH 960 VRKRRKTTAE EKEAGEERLE KREQVDEQVE ENLKNNAVLP SPSPQKEGRR RRTVCAVPSA 1020 RASRPRKTRA DPEDETSFPE TAGDQESCML SGQTSASPSL PLRSRQKSRW IEEDSVSGPL 1080 PHPRASRPSS FFVAETGRIG VGGAQPRRSC SALMSTTSVD LEGGGELFGN RERGPPRRRQ 1140 SASFLAAPAA PAIVVHQVSP APGAGERPRK KESLAVNKKS EATFSSSVVS AATPVDTPFL 1200 MYFDMKREYP ATSALRDPEA NGDLRPGEED ALPRGGVYVQ PSAGAPSEAR EALGRVRVRE 1260 EEARRVESSR GFAVLPPVPA APEEQRDIRV FLNRAGIHLL NLFFPRDSHS YVGKTPLQPL 1320 LRSYPQELLL GLKYILSSHY LPLLSFPDVY TLQELSLSPH LSPPLQLLLS IIFEELARTN 1380 LTYKYQQYGE LGFDENLCHP GKVLFDGGPG CQAIHAAEFR VFWMRRHGRR LGRRRPGWGS 1440 RAQLAVGSRA DDAPVAPFQS PPPPLPLASP QASGLERERL FSGKKFERRD PRDAFSGACT 1500 LDGLDHDSPP GASPCTSPKQ AEFPPPTPQF VETPDRVRGL AGLFEGSPRS AFSAAENGDH 1560 STSLSTVFDL LEPARLHPLA ASFDGDTFGA AGPEKSLLKI SGKAPENGRP LQCTCGRDEA 1620 ERRRQLPGER PSKPPLREKK PLDAETKKNS ADGSRTADGA PAPELSEVPT GQPPPLPSAE 1680 KSGAELFATP APFRWMKKAL GAVRSQGISG LKKETVPRNL DFYFRLNRRA SDDAAQLQAK 1740 ADSAKRGETS TARAESTGGL NAAGPLAAGE EFQGLSDAGK DETDVASKNR ETPGGGVSRS 1800 SVDSRSLSER RDSEVSVSAP ADDRDSQDEV VAVSRPSALT GRGGLYSAVS SPALSASDFA 1860 EELSENEARP VVLRTNGHRP EVRPAEPRRE EEGDTFGPPA WAPKGEAPGS EEGKATRDDE 1920 EKAGREKAPV PRCASTPQDR FVVSWDDDEW LGSIECFLDD LSLCPSAVST RACSFESSST 1980 HGASCPLASR GAPHTRSLPA DFVLHPPLLP PSLSPSAPPS SVSLSAVSAP LVPASPCVGG 2040 AGVQTPGPCS CREVIVVDVQ SDAQLRKRIW DVQTLFTGSE LSVHRKIELL RRMVLRSIKS 2100 AATGYGEQKD EVKRLAAEHD GFVYLGDVNY GFSRHMALLF KVLCDASQIP CRVMRAGLLG 2160 EETVGDNGDT SARSPELGGG APGEGEKRLA GPRARRDGLE RQERRRREEE EFVYNVVLVK 2220 DATKSELEQL IPIIWTQNAA AGLWRRYLSP GVEKGARGED RERKRGRHSS LTDFLASGVV 2280 RLNPPTLSSI PLPRRLRALQ RRLAVSSASF SSCGQERSSE RSRCVERDLE TETGRGATAG 2340 NERCGDTAGD LGGDRELPPL GRARSPRPFD YFKHGWVDRR RETSHCCCCA SRSLPSLEAE 2400 TGGDRAETRG DNGRDNRVGR DSAPGGDVTS RNESSEKTEK ENWGAKPSED GPLHRQHADL 2460 DRLLLAASGA SAFCGCGGAP ASVAATELDL DAFFDFREKL GKGSFGEVWR VRIKSEGRAV 2520 GAARRKPRER KRSREEQDAG VREENAVSEE EERGKEVHSG EERAEAPWRR ETDEDGEADE 2580 AGERGEADEA CRGDSGEPAE PEYALKLVPK SEENLPEAEI MRSYSHPRVV PFLGVFEGFQ 2640 MLEDRSKKKV KNTSLCFLMD IADQSLESLL EEHEKANTCL DVEFILTILL DTARGMNYLH 2700 SPSATKPHLL HRDLKPANIL LKDGRAMVTD FGVARVAEVS FEHEMTQGPG TEGYIAPEQR 2760 TAAYDRPADV WAFGVVCARL LGLREWKKLS DPQHRVALSD FALKDAFLIN LCLACLERRP 2820 LMRPTFHQIV QRLIDKIFRL EFERILRTPY RNCLPLLHAE NPLVFSSPAS LPVGRGDTPS 2880 RAVETVDVRR LGEKSGAITP FRSPSLCPSQ LAPPARPVPS RLSRSLLEAP FSAGGENVEA 2940 LASRTEKVSP KARPEEGVCS GRPASACTHR SGNDEAAAPA SSLSTGGEEE VFFSGEESEA 3000 TSQAKNAEAK GEPQLGPVAD PEVTEDQEEE GFFSRLRLRT MKRSRPLLLS SSEVSPASSE 3060 REDAAEECDG AVEPDTNAKE KKLETKSESN EKSQEKREEV DPVDGVVTPH RLSPSDKKEP 3120 KEPSLLKKSG VSPLQKKQAS PASKKKVWKT PTSFVSLRTP DKVAANSSSS SSSSSSSSSS 3180 SSSSSSSSSS SASSSPSSPS SAASASLSPT GGSRRRAASP QREREERRRP GRTSPKLTPR 3240 GREEERRLSP TEKDDRGQSL SRGRSVSRGR CLGKEGEKIR TKERNAEKTP TQTPNHRRRS 3300 PSPSLSTSPL SRFDEAGVQD AEEGVLRHPS SRGPRSKISE NPRISACSPS SPFSPCPSPS 3360 SASSPSAFSS LSASVLKNRV GSVDAQRSLG ERKGLLLSSS ASVGSETRDA RRSPEGVSAV 3420 SSEGSASLSG APRVLASRQA DSSSDSLVET EISHAPNCAS SAFPPPARVA GLAAPFAAKP 3480 ATQTAPIRKG DSFSDAYKVS GATEQLASGG NEGRGSGSLS 3520 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:InterPro. GO:0004382; F:guanosine-diphosphatase activity; IEA:EC. GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |