CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029207
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Epidermal growth factor receptor pathway substrate 15 
Protein Synonyms/Alias
  
Gene Name
 Eps15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
413AQLEEQLKEVRKKCAubiquitination[1]
817FPGNDSPKEKDPDMFubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Receptor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 897 AA 
Protein Sequence
MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGVLNK QEFFIALRLV ACAQNGLEVS LSSLNLAVPP PRFHDSSSPL LTSGTSVAEL 120
PWAVKSEDKA KYDAIFDSLS PVDGFLSGDK VKPVLLNSKL PVEILGRVWE LSDIDHDGKL 180
DRDEFAVAMF LVYCALEKEP VPMSLPPALV PPSKRKTWVV SPAEKAKYDE IFLKTDKDMD 240
GYVSGLEVRE TFLKTGLPST LLAHIWALCD TKNCGKLSKD QFALAFHLIN QKLIKGIDPP 300
HSLTPEMIPP SDRSSLQKNT IGSSPVADFS AIKELDTLNN EIIDLQREKN NVEQDLKEKE 360
DTVRQRTTEA QDLQDEVQRE SLNLQKLQAQ KQQVQELLDE LDEQKAQLEE QLKEVRKKCA 420
EEAQLISSLK AEITSQESQI STYEEELSKA REELSRLQQE TAQLEESVES GKAQLEPLQQ 480
HLQDSQQEIS SMQMRLAMKD LETDNNQSNW CSSPQSILVN GAADYCSLST SSSETANLNE 540
HAEGQNNLES EPIHPESSVR SSPEIAPSDV TDESEVVTAA DIEKVSPRFD DDKHSKEEDP 600
FNVESSSLTD AVADTNLDFF QSDPFVGSDP FKDDPFGKID PFGGDPFKGS DPFASDCFFK 660
QTSTDPFATS STDPFSASSN SSNTSVETWK HNDPFAPGGT VVAATDSATD PFASVFGNES 720
FGDGFADFST LSKVSNEDPF NPTISSSASS VVIPKPVLEE TPSKSEDVPP ALPPKTGTPT 780
RPCPPPPGKR PINKLDSSDP FKLNDPFQPF PGNDSPKEKD PDMFCDPFTS SSTTANKEAE 840
PSNFANFSAY PSEEDMIEWA KRESEREEEQ RLARLNQQEQ EDLELAIALS KSEISEA 897 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology.
 IPR003903; Ubiquitin-int_motif. 
Pfam
  
SMART
 SM00054; EFh
 SM00027; EH
 SM00726; UIM 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH
 PS50330; UIM 
PRINTS