CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035053
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Sppl2a 
Protein Synonyms/Alias
 Similar to RIKEN cDNA 2010106G01 (Predicted) 
Gene Name
 Sppl2a 
Gene Synonyms/Alias
 RGD1563001_predicted; rCG_26538 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
103GPCHFLEKAKIAQEGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 523 AA 
Protein Sequence
MGLLHSLHAP AAALLWSCLL GLSAAQEAIL HASANGVSSL SKDYCMYYNN NWTRLPSSLE 60
NATSLSLMNL TGTPLCHLSD IPPDGIKNKA VVVHWGPCHF LEKAKIAQEG GAAALLIANN 120
SVLIPSSRNK SAFQNVTILI AVITQKDFND MKETLGDDIT VKMYSPSWPN FDYTLVVIFV 180
IAVFTVALGG YWSGLIELES MKAVEDAEDR EARKKKEDYL TFSPLTVVLF VVICCVMIVL 240
LYFFYKWLVY VMIAIFCIAS ATSLYNCLAA LIHRMPCGQC TILCCGKNIK VSLIFLSGLC 300
ISVAVVWAVF RNEDRWAWIL QDILGIAFCL NLIKTMKLPN FMSCVILLGL LLIYDVFFVF 360
ITPFITKNGE SIMVELAAGP FENAEKLPVV IRVPKLMDYS VMSVCSVPVS VLGFGDIIVP 420
GLLIAYCRRF DVQTGSSIYY ISSTIAYAVG MIITFVVLMV MKTGQPALLY LVPCTLITAS 480
IVAWSRKEMK KFWKGSSYQV MDYLDYSTNE ENPAATDEQI VQQ 523 
Gene Ontology
 GO:0030660; C:Golgi-associated vesicle membrane; IEA:Compara.
 GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IEA:Compara.
 GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IEA:Compara.
 GO:0031902; C:late endosome membrane; IEA:Compara.
 GO:0005765; C:lysosomal membrane; IEA:Compara.
 GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
 GO:0006509; P:membrane protein ectodomain proteolysis; IEA:Compara.
 GO:0031293; P:membrane protein intracellular domain proteolysis; IEA:Compara.
 GO:0050776; P:regulation of immune response; IEA:Compara. 
Interpro
 IPR006639; Peptidase_A22.
 IPR007369; Peptidase_A22B_SPP.
 IPR003137; Protease-assoc_domain. 
Pfam
 PF02225; PA
 PF04258; Peptidase_A22B 
SMART
 SM00730; PSN 
PROSITE
  
PRINTS