CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038082
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutathione S-transferase Mu 6 
Protein Synonyms/Alias
  
Gene Name
 Gstm5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
6**MDGKNKITQSNAIubiquitination[1]
20ILRYIARKHNMCGDTacetylation[2]
61NSNHENLKPQYLEQLacetylation[2]
61NSNHENLKPQYLEQLubiquitination[1]
110QNRIFEPKCLDEFPNubiquitination[1]
130CRFEALEKIAAFLQSacetylation[2]
142LQSDRFFKMPINNKMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 158 AA 
Protein Sequence
MDGKNKITQS NAILRYIARK HNMCGDTEEE KIRVDIMENQ IMDFRMQLVR LCYNSNHENL 60
KPQYLEQLPA QLKQFSLFLG KFTWFAGEKL TFVDFLTYDV LDQNRIFEPK CLDEFPNLKA 120
FMCRFEALEK IAAFLQSDRF FKMPINNKMA KWGNKCLC 158 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0043295; F:glutathione binding; IEA:Compara.
 GO:0004364; F:glutathione transferase activity; IDA:MGI.
 GO:0042803; F:protein homodimerization activity; IDA:MGI.
 GO:0070458; P:cellular detoxification of nitrogen compound; IEA:Compara.
 GO:0006749; P:glutathione metabolic process; IEA:Compara.
 GO:0018916; P:nitrobenzene metabolic process; IEA:Compara.
 GO:0043627; P:response to estrogen stimulus; IEA:Compara.
 GO:0042178; P:xenobiotic catabolic process; IEA:Compara. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR003081; GST_mu.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF00043; GST_C 
SMART
  
PROSITE
 PS50405; GST_CTER
 PS50404; GST_NTER 
PRINTS
 PR01267; GSTRNSFRASEM.