UniProt Accession

 PDXH_SALTY; Q8ZPM9 

Genbank Protein ID

 AE006468 

Genbank Nucleotide ID

 AAL20370.1 

Protein Name

 Pyridoxine/pyridoxamine 5'-phosphate oxidase 

Protein Synonyms/Alias

 PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase 

Gene Name

 pdxH 

Gene Synonyms/Alias

 STM1448 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
61	VVATVDDKGQPYQRI	acetylation	[1]
72	YQRIVLLKHYDEKGL	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity). 

Sequence Annotation

 NP_BIND 82 83 FMN (By similarity).
 NP_BIND 146 147 FMN (By similarity).
 REGION 14 17 Substrate binding (By similarity).
 REGION 197 199 Substrate binding (By similarity).
 BINDING 67 67 FMN (By similarity).
 BINDING 70 70 FMN; via amide nitrogen (By similarity).
 BINDING 72 72 Substrate (By similarity).
 BINDING 89 89 FMN (By similarity).
 BINDING 129 129 Substrate (By similarity).
 BINDING 133 133 Substrate (By similarity).
 BINDING 137 137 Substrate (By similarity).  

Keyword

 Complete proteome; Flavoprotein; FMN; Oxidoreductase; Pyridoxine biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0010181; F:FMN binding; IEA:HAMAP.
 GO:0004733; F:pyridoxamine-phosphate oxidase activity; IEA:HAMAP.
 GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:GOC.
 GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW. 

Interpro

 IPR000659; Pyridox_Oxase.
 IPR019740; Pyridox_Oxase_CS.
 IPR011576; Pyridox_Oxase_FMN-bd.
 IPR019576; Pyridoxamine_oxidase_dimer_C.
 IPR012349; Split_barrel_FMN-bd. 

Pfam

 PF10590; PNPOx_C
 PF01243; Pyridox_oxidase 

SMART

  

PROSITE

 PS01064; PYRIDOX_OXIDASE 

PRINTS