| Tag | Content |
|---|
| CPLM ID | CPLM-009238 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Lipid A export ATP-binding/permease protein MsbA |
Protein Synonyms/Alias | |
Gene Name | msbA |
Gene Synonyms/Alias | b0914; JW0897 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 118 | MPVSFFDKQSTGTLL | acetylation | [1] | | 232 | VETKRFDKVSNRMRL | acetylation | [1] | | 528 | AALDELQKNRTSLVI | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. |
Sequence Annotation | DOMAIN 27 310 ABC transmembrane type-1.
DOMAIN 342 578 ABC transporter.
NP_BIND 376 383 ATP (By similarity). |
Keyword | 3D-structure; ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Hydrolase; Lipid transport; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 582 AA |
Protein Sequence | MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD 60
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS 120
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI 180
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ 240
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS 300
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR 360
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA 420
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL 480
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS 540
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ 582 |
Gene Ontology | GO:0016021; C:integral to membrane; IBA:RefGenome. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IDA:EcoCyc. GO:0008144; F:drug binding; IDA:EcoliWiki. GO:0008289; F:lipid binding; IDA:EcoliWiki. GO:0034040; F:lipid-transporting ATPase activity; IDA:EcoliWiki. GO:0015437; F:lipopolysaccharide-transporting ATPase activity; IDA:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |