| Tag | Content |
|---|
| CPLM ID | CPLM-016455 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation of very long chain fatty acids protein 5 |
Protein Synonyms/Alias | 3-keto acyl-CoA synthase Elovl5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Very-long-chain 3-oxoacyl-CoA synthase 5 |
Gene Name | Elovl5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 292 | PSLENSVKPRKQRKD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids (By similarity). |
Sequence Annotation | MOD_RES 273 273 Phosphoserine.
MOD_RES 281 281 Phosphothreonine.
MOD_RES 283 283 Phosphoserine. |
Keyword | Complete proteome; Endoplasmic reticulum; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Membrane; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 299 AA |
Protein Sequence | MEHFDASLST YFKAFLGPRD TRVKGWFLLD NYIPTFVCSV IYLLIVWLGP KYMKNRQPFS 60
CRGILQLYNL GLTLLSLYMF YELVTGVWEG KYNFFCQGTR SAGESDMKII RVLWWYYFSK 120
LIEFMDTFFF ILRKNNHQIT VLHVYHHATM LNIWWFVMNW VPCGHSYFGA TLNSFIHVLM 180
YSYYGLSSIP SMRPYLWWKK YITQGQLVQF VLTIIQTTCG VFWPCSFPLG WLFFQIGYMI 240
SLIALFTNFY IQTYNKKGAS RRKDHLKGHQ NGSVAAVNGH TNSFPSLENS VKPRKQRKD 299 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0009922; F:fatty acid elongase activity; ISS:UniProtKB. GO:0034625; P:fatty acid elongation, monounsaturated fatty acid; ISS:UniProtKB. GO:0034626; P:fatty acid elongation, polyunsaturated fatty acid; ISS:UniProtKB. GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |