CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013722
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Catalase-peroxidase 
Protein Synonyms/Alias
 CP; Peroxidase/catalase 
Gene Name
 katG 
Gene Synonyms/Alias
 GK1710 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
2******MKNQNQHNTacetylation[1]
70KLDYWALKEDLRKLMacetylation[1]
145RRLLWPIKKKYGNKIacetylation[1]
196DIYWGAEKEWLASERacetylation[1]
232NPEGPDGKPDPVAAAacetylation[1]
387RFDPEYEKIARRFYEacetylation[1]
428YLGPEVPKEDFIWQDacetylation[1]
524IQRELPKKVSIADLIacetylation[1]
587GFRNYQKKEYSVGPEacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity). 
Sequence Annotation
 ACT_SITE 101 101 Proton acceptor (By similarity).
 METAL 264 264 Iron (heme axial ligand) (By similarity).
 CROSSLNK 100 223 Tryptophyl-tyrosyl-methioninium (Trp-Tyr)
 CROSSLNK 223 249 Tryptophyl-tyrosyl-methioninium (Tyr-Met)  
Keyword
 Complete proteome; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 736 AA 
Protein Sequence
MKNQNQHNTS KCPYHGSVTS YNSNRTTNKD WWPNQLNLSI LHQHDRKTNP HDEEFNYAEE 60
FQKLDYWALK EDLRKLMTES QDWWPADYGH YGPLFIRMAW HSAGTYRIGD GRGGGSTGTQ 120
RFAPLNSWPD NANLDKARRL LWPIKKKYGN KISWADLMIL AGNVAIESMG GKTIGFGGGR 180
EDVWHPEEDI YWGAEKEWLA SERYSGDREL ENPLAAVQMG LIYVNPEGPD GKPDPVAAAR 240
DIRETFRRMG MNDEETVALI AGGHTFGKAH GAGPASHVGP EPEAAPIEAQ GLGWISSYGK 300
GKGRDTITSG IEGAWTPTPT QWDNSYFRLL FEYEWKLTKS PAGAYQWEAV NLREEDLAPD 360
AEDPNVKVPP MMMTTDLALR FDPEYEKIAR RFYENPEEFA DAFARAWFKL THRDMGPKTR 420
YLGPEVPKED FIWQDPIPTV DYELSDAEIE EIKAKILNSG LTVSELVKTA WASASTFRNS 480
DKRGGANGAR IRLAPQKDWE VNEPERLAKV LSVYEDIQRE LPKKVSIADL IVLGGSAAVE 540
KAARDAGFDV KVPFIPGRGD ATQEQTDVES FSVLEPFADG FRNYQKKEYS VGPEELLIDK 600
AQLLGLTAPE MTVLVGGLRV LGANYRDLPH GVFTDRIGVL TNDFFVNLVD MNYEWVPTEG 660
GIYEIRDRQT GEVRWTATRV DLIFGANSIL RSYAEFYAQD DNREKFVRDF INAWVKVMNA 720
DRFDIHLKQA KESVTV 736 
Gene Ontology
 GO:0004096; F:catalase activity; IEA:HAMAP.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR000763; Catalase_peroxidase.
 IPR010255; Haem_peroxidase.
 IPR002016; Haem_peroxidase_pln/fun/bac.
 IPR019794; Peroxidases_AS.
 IPR019793; Peroxidases_heam-ligand_BS. 
Pfam
 PF00141; peroxidase 
SMART
  
PROSITE
 PS00435; PEROXIDASE_1
 PS00436; PEROXIDASE_2
 PS50873; PEROXIDASE_4 
PRINTS
 PR00460; BPEROXIDASE.
 PR00458; PEROXIDASE.