CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039987
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 HEAT repeat-containing protein 5A 
Protein Synonyms/Alias
  
Gene Name
 HEATR5A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
296RASGDMLKGTSSVSRubiquitination[1]
623AGALCAIKSFVSHCGubiquitination[1]
1601DVPWPRSKIGSDQDLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2046 AA 
Protein Sequence
MELAHSLLLN EEAYNQLGEV QKAEFIFEWL RYLEKLLLAT SRNDVREKQK TLVEQLLSLL 60
NSSPGPPTRK LLAKNLAILY SIGDTFSVHE AIDKCNDLIR SKDDSPSYLP TKLAAVVCLG 120
SLYKKLGRIL GNTFTDTVGN ILKAMKSAES QGRYEIMLSL QNILNGLGAA AAPCHRDVYK 180
AARSCLTDRS MAVRCAAAKC LLELQNEAIF MWSTDLDSVA TLCFKSFEGS NYDVRISVSK 240
LLGIILAKAV ISKHPGTAAS RQSIRRVSLE EVLELLGTGF LRGSSGFLRA SGDMLKGTSS 300
VSRDVRVGVT QAYVVFVSTL GGAWLEKNFA AFFSHILSLA SPSHPKATQT QIDAVCCRRC 360
VSFILRTTIG GLLGEKAQLA AVKDICQAIW KLKKVMDAVM SDGNLETRLG STDVAASQHM 420
LVCALQELGN LIHNLGTTAA PLLQDSSTGL LDSILSVILH PSISVRLAAA WCLHCIAVAL 480
PSYLTPLLDR CLERLTGHKS SPEAVTGFSF AVAALLGAVK HCPLGIPHGK GKIIMTLAED 540
LLCSAAQNSR LSAQRTQAGW LLISALMTLG PAVVSHHLAR VLLLWKCVFP ASPKDLETEK 600
SRGDSFTWQV TLEGRAGALC AIKSFVSHCG DLLTEEVTQR LLPPLPCAVD LLTQLSSILK 660
MYGSPLKTPS VVYRQRLYEL LILLPPETYE GNLCAILREL AADLTAPDIQ VAASTFLLPP 720
LCHQDDLLIL SPFLQETDHR FIEEQLLLGN GVACGSLEYD PYSIYEKDVE GDSVPKPLPP 780
ALSVISSASK LFGVVCAHVG ETQRLLILEQ LLDSIKHTKG ARQQVVQLHV VSSVSSFLKY 840
VAGSKGCLGP EEMKRFALTL VMGALESPNP LLRCAAAESW ARLAQVVDDG AFTAGLAQVS 900
FDKLKSARDV VTRTGHSLAL GSLHRYLGGI SSSQHLNSCI GILYTLAQDS TSPDVQTWAL 960
HSLSLIIDSA GPLYYVHVEP TLSLIIMLLL NVPPTHAEVH QSLGRCLNAL ITTLGPELQG 1020
NSTSISTLRT SCLLGCAVMQ DNPDCLVQAQ AISCLQQLHM FAPRHVNLSS LVSCLCVNLC 1080
SPYLLLRRAV LACLRQLVQR EAAEVSEHAV MLAKDSREEL TPDANIREVG LEGALLILLD 1140
KETDERLCHD IKETLNYMLT SMAVEKLSLW LKLCKDVLAA SADFTAVTCV DTMQEEEGDK 1200
GDDASVLTTR RDEKSHPFTN PRWATRVFAA ECVCRIINQC ENANSAHFDI ALAQEMKKRD 1260
SRNDFLVLHL ADLIRMAFMA ATDHSDQLRL SGLEMLLVVI RRFATVPEPE FPGHVILEQY 1320
QANVGAALRP AFTSETPPDV TAKACQVCSA WIASGVVSDL NDLRRVHQLL VSSLTKIQAG 1380
KEALSHLYNE SASTMEILAV LKAWAEVYII AVQRHKNHRQ PLKTTTCLED GIRNGSCSSD 1440
GLLDLVYADL GTLSRLWLAA LQDFALLTLP SEFASQLPAE GGAFYTAETS ENAKLHYYNS 1500
WALILHATAL WLTSTGFVVA DPDEGASNLS RPVTPTSMCQ GSSSGATIKS PEDVYTDRFH 1560
LILGISVEFL CSLRSDATME SITACLHALQ ALLDVPWPRS KIGSDQDLGI ELLNVLHRVI 1620
LTRESPSIQL ASLEVVRQII CAAQEHVKEK RRSAEVDDGA AEKETLPEFG EGKDTGGLVP 1680
GKSLVFATLE LCVCILVRQL PELNPKLTGS PGVKATKPQI LLEDGSRLVS AALVILSELP 1740
AVCSPEGSIS ILPTILYLTI GVLRETAVKL PGGQLSSTVA ASLQALKGIL SSPMARAEKS 1800
RTAWTDLLRS ALTTILDCWD PVDETHQELD EVSLLTAITV FILSTSPEVT TIPCLQKRCI 1860
DKFKATLEIK DPVVQIKTYQ LLHSIFQYPN PAVSYPYIYS LASCIMEKLQ EIDKRKPENT 1920
AELEIFQEGI KVLETLVTVA EEHHRAQLVA CLLPILISFL LDENSLGSAT SIMRNLHDFA 1980
LQNLMQIGPQ YSSVFKSLVA SSPALKARLE AAIKGNQESV KVKIPTSKYT KSPGKNSSIQ 2040
LKTSFL 2046 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
  
SMART
  
PROSITE
  
PRINTS