CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031423
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PCNA-interacting partner 
Protein Synonyms/Alias
 cDNA FLJ57674 
Gene Name
 PARPBP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MAVFNQKSVSDMIKubiquitination[1, 2]
100KIYDDFLKNSNMLDLubiquitination[3, 4]
113DLIDVYQKCRALTSNubiquitination[2, 4]
235IPTSPTSKYNRDNEKubiquitination[2, 3, 4]
287REAFTDLKHAAREKQubiquitination[2]
431YCGRDTVKALLVLLDubiquitination[3]
447EAANAPTKNKAELLYubiquitination[3]
482TQVNNSIKPLRERICubiquitination[3]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 656 AA 
Protein Sequence
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL 60
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN 120
CENYNTVSPG STIQPPSERG SLLLSRPDLL APGEDPPVSA SLTLERQKGE SLLAWSWSLN 180
FRLPGIPITV QKKRRDLKKL AAVMRQSQLL DFLSGKQYAV GDETDLSIPT SPTSKYNRDN 240
EKVQLLARKI IFSYLNLLVN SKNDLAVAYI LNIPDRGLGR EAFTDLKHAA REKQMSIFLV 300
ATSFIRTIEL GGKGYAPPPS DPLRTHVKGL SNFINFIDKL DEILGEIPNP SIAGGQILSV 360
IKMQLIKGQN SRDPFCKAIE EVAQDLDLRI KNIINSQEGV VALSTTDISP ARPKSHAINH 420
GTAYCGRDTV KALLVLLDEE AANAPTKNKA ELLYDEENTI HHHGTSILTL FRSPTQVNNS 480
IKPLRERICV SMQEKKIKMK QTLIRSQFAC TYKDDYMISK DNWNNVNLAS KPLCVLYMEN 540
DLSEGVNPSV GRSTIGTSFG NVHLDRSKNE KVSRKSTSQT GNKSSKRKQV DLDGENILCD 600
NRNEPPQHKN AKIPKKSNDS QNRLYGKLAK VAKSNKCTAK DKLISGQAKL TQFFRL 656 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR027417; P-loop_NTPase. 
Pfam
  
SMART
  
PROSITE
  
PRINTS