CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040684
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 60S acidic ribosomal protein P0 
Protein Synonyms/Alias
  
Gene Name
 RPLP0 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
228YTFPLAEKVKAFLADubiquitination[1, 2]
230FPLAEKVKAFLADPSubiquitination[1, 2, 3, 4]
261AAAAAPAKVEAKEESubiquitination[1, 2, 3]
265APAKVEAKEESEESDubiquitination[3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 281 AA 
Protein Sequence
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM 60
MRKAIRGHLE NNPALEKLLP HIRGNVGFVF TKEDLTEIRD MLLANKVPAA ARAGAIAPCE 120
VTVPAQNTGL GPEKTSFFQA LGITTKISRG TIEILVFDNG SIYNPEVLDI TEETLHSRFL 180
EGVRNVASVC LQIGYPTVAS VPHSIINGYK RVLALSVETD YTFPLAEKVK AFLADPSAFV 240
AAAPVAAATT AAPAAAAAPA KVEAKEESEE SDEDMGFGLF D 281 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0042254; P:ribosome biogenesis; IEA:InterPro.
 GO:0006414; P:translational elongation; IEA:InterPro. 
Interpro
 IPR001790; Ribosomal_L10/acidic_P0.
 IPR001813; Ribosomal_L10/L12. 
Pfam
 PF00428; Ribosomal_60s
 PF00466; Ribosomal_L10 
SMART
  
PROSITE
  
PRINTS