| Tag | Content |
|---|
| CPLM ID | CPLM-007745 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transketolase |
Protein Synonyms/Alias | TK |
Gene Name | tkt |
Gene Synonyms/Alias | tktA; BSU17890 |
Created Date | July 27, 2013 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 268 | VHGAPLGKEESKLTK | acetylation | [1] | | 275 | KEESKLTKEAYAWTY | acetylation | [1] | | 339 | AIKGELPKDWDQEVP | acetylation | [1] |
|
Reference | [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis. Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG. Proteomics. 2013 May;13(10-11):1726-36. [ PMID: 23468065] |
Functional Description | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity). |
Sequence Annotation | NP_BIND 115 117 Thiamine pyrophosphate (By similarity).
ACT_SITE 411 411 Proton donor (By similarity).
METAL 156 156 Magnesium (By similarity).
METAL 186 186 Magnesium (By similarity).
METAL 188 188 Magnesium; via carbonyl oxygen (By
BINDING 27 27 Substrate (By similarity).
BINDING 67 67 Thiamine pyrophosphate (By similarity).
BINDING 157 157 Thiamine pyrophosphate; via amide
BINDING 186 186 Thiamine pyrophosphate (By similarity).
BINDING 262 262 Substrate (By similarity).
BINDING 262 262 Thiamine pyrophosphate (By similarity).
BINDING 357 357 Substrate (By similarity).
BINDING 384 384 Substrate (By similarity).
BINDING 437 437 Thiamine pyrophosphate (By similarity).
BINDING 461 461 Substrate (By similarity).
BINDING 469 469 Substrate (By similarity).
BINDING 520 520 Substrate (By similarity). |
Keyword | Calcium; Complete proteome; Magnesium; Metal-binding; Reference proteome; Thiamine pyrophosphate; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 667 AA |
Protein Sequence | MDTIEKKSVA TIRTLSIDAI EKANSGHPGM PMGAAPMAYT LWTKFMNVSP ANPGWFNRDR 60
FVLSAGHGSA LLYSMLHLSG FDLSIEDLKG FRQWGSKTPG HPEFGHTAGV DATTGPLGQG 120
IAMAVGMAIA ERHLAETYNR DSFNVVDHYT YSICGDGDLM EGISSEAASL AGHLQLGRLI 180
VLYDSNDISL DGDLDRSFSE NVKQRFEAMN WEVLYVEDGN NIEELTAAIE KARQNEKKPT 240
LIEVKTTIGF GSPNRAGTSG VHGAPLGKEE SKLTKEAYAW TYEEDFYVPS EVYEHFAVAV 300
KESGEKKEQE WNAQFAKYKE VYPELAEQLE LAIKGELPKD WDQEVPVYEK GSSLASRASS 360
GEVLNGLAKK IPFFVGGSAD LAGSNKTTIK NAGDFTAVDY SGKNFWFGVR EFAMGAALNG 420
MALHGGLRVF GGTFFVFSDY LRPAIRLAAL MGLPVTYVFT HDSIAVGEDG PTHEPVEQLA 480
SLRAMPNLSL IRPADGNETA AAWKLAVQST DHPTALVLTR QNLPTIDQTS EEALAGVEKG 540
AYVVSKSKNE TPDALLIASG SEVGLAIEAQ AELAKENIDV SVVSMPSMDR FEKQSDEYKN 600
EVLPADVKKR LAIEMGSSFG WGKYTGLEGD VLGIDRFGAS APGETIINEY GFSVPNVVNR 660
VKALINK 667 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |