UniProt Accession

 HMMR_MOUSE; Q00547; Q5NC88 

Genbank Protein ID

 AF031932; AF079222; AL646055; CH466609; AJ005919; AJ005920; AJ005921; AJ005922; AJ005923; AJ005924; X64550; X64550 

Genbank Nucleotide ID

 AAC12655.1; AAD08670.1; CAI25425.1; EDL32330.1; CAA06768.1; CAA06768.1; CAA06768.1; CAA06768.1; CAA06768.1; CAA06768.1; CAA45849.1; CAA45848.1 

Protein Name

 Hyaluronan mediated motility receptor 

Protein Synonyms/Alias

 Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility; CD168 

Gene Name

 Hmmr 

Gene Synonyms/Alias

 Ihabp; Rhamm 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
9	SFPKAPLKRFNDPSG	acetylation	[1]
625	LEKITDLKNQLRQQD	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity. 

Sequence Annotation

 REPEAT 442 462 1.
 REPEAT 463 483 2.
 REPEAT 484 504 3.
 REPEAT 505 525 4.
 REPEAT 526 546 5.
 REGION 442 546 5 X 21 AA tandem repeats.
 REGION 719 729 Hyaluronic acid-binding (Potential).
 REGION 741 750 Hyaluronic acid-binding (Potential).
 MOD_RES 20 20 Phosphoserine (By similarity).
 CARBOHYD 134 134 N-linked (GlcNAc...) (Potential).
 CARBOHYD 279 279 N-linked (GlcNAc...) (Potential).
 CARBOHYD 446 446 N-linked (GlcNAc...) (Potential).
 CARBOHYD 467 467 N-linked (GlcNAc...) (Potential).
 CARBOHYD 488 488 N-linked (GlcNAc...) (Potential).
 CARBOHYD 509 509 N-linked (GlcNAc...) (Potential).
 CARBOHYD 530 530 N-linked (GlcNAc...) (Potential).
 CARBOHYD 561 561 N-linked (GlcNAc...) (Potential).
 CARBOHYD 601 601 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Glycoprotein; Hyaluronic acid; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 794 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW. 

Interpro

 IPR026203; IHABP. 

Pfam

  

SMART

  

PROSITE

  

PRINTS