CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019540
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trafficking protein particle complex subunit 9 
Protein Synonyms/Alias
 NIK- and IKBKB-binding protein; Tularik gene 1 protein 
Gene Name
 TRAPPC9 
Gene Synonyms/Alias
 KIAA1882; NIBP; T1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
103FEKFHVQKEIYGSTLubiquitination[1]
146EDCQTVEKRIEDFIEubiquitination[1]
446YSLSLDPKDFSRGTHubiquitination[1]
544LPIVRHVKLLNLPASubiquitination[2]
558SLRPHKMKSLLGQNVubiquitination[1, 2]
568LGQNVSTKSPFIYSPubiquitination[1]
761KVLTTKEKLYGDFLSubiquitination[1]
835VRPRVEGKPVNPPESubiquitination[1]
844VNPPESNKAGDYSHVubiquitination[1]
852AGDYSHVKTLEAVLNubiquitination[3]
944RMAIQVDKFNFESFPubiquitination[1, 2]
957FPESPGEKGQFANPKubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Differentiation; Endoplasmic reticulum; Golgi apparatus; Mental retardation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1148 AA 
Protein Sequence
MSVPDYMQCA EDHQTLLVVV QPVGIVSEEN FFRIYKRICS VSQISVRDSQ RVLYIRYRHH 60
YPPENNEWGD FQTHRKVVGL ITITDCFSAK DWPQTFEKFH VQKEIYGSTL YDSRLFVFGL 120
QGEIVEQPRT DVAFYPNYED CQTVEKRIED FIESLFIVLE SKRLDRATDK SGDKIPLLCV 180
PFEKKDFVGL DTDSRHYKKR CQGRMRKHVG DLCLQAGMLQ DSLVHYHMSV ELLRSVNDFL 240
WLGAALEGLC SASVIYHYPG GTGGKSGARR FQGSTLPAEA ANRHRPGAQE VLIDPGALTT 300
NGINPDTSTE IGRAKNCLSP EDIIDKYKEA ISYYSKYKNA GVIELEACIK AVRVLAIQKR 360
SMEASEFLQN AVYINLRQLS EEEKIQRYSI LSELYELIGF HRKSAFFKRV AAMQCVAPSI 420
AEPGWRACYK LLLETLPGYS LSLDPKDFSR GTHRGWAAVQ MRLLHELVYA SRRMGNPALS 480
VRHLSFLLQT MLDFLSDQEK KDVAQSLENY TSKCPGTMEP IALPGGLTLP PVPFTKLPIV 540
RHVKLLNLPA SLRPHKMKSL LGQNVSTKSP FIYSPIIAHN RGEERNKKID FQWVQGDVCE 600
VQLMVYNPMP FELRVENMGL LTSGVEFESL PAALSLPAES GLYPVTLVGV PQTTGTITVN 660
GYHTTVFGVF SDCLLDNLPG IKTSGSTVEV IPALPRLQIS TSLPRSAHSL QPSSGDEIST 720
NVSVQLYNGE SQQLIIKLEN IGMEPLEKLE VTSKVLTTKE KLYGDFLSWK LEETLAQFPL 780
QPGKVATFTI NIKVKLDFSC QENLLQDLSD DGISVSGFPL SSPFRQVVRP RVEGKPVNPP 840
ESNKAGDYSH VKTLEAVLNF KYSGGPGHTE GYYRNLSLGL HVEVEPSVFF TRVSTLPATS 900
TRQCHLLLDV FNSTEHELTV STRSSEALIL HAGECQRMAI QVDKFNFESF PESPGEKGQF 960
ANPKQLEEER REARGLEIHS KLGICWRIPS LKRSGEASVE GLLNQLVLEH LQLAPLQWDV 1020
LVDGQPCDRE AVAACQVGDP VRLEVRLTNR SPRSVGPFAL TVVPFQDHQN GVHNYDLHDT 1080
VSFVGSSTFY LDAVQPSGQS ACLGALLFLY TGDFFLHIRF HEDSTSKELP PSWFCLPSVH 1140
VCALEAQA 1148 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. 
Interpro
 IPR013935; TRAPP_II_complex_Trs120. 
Pfam
 PF08626; TRAPPC9-Trs120 
SMART
  
PROSITE
  
PRINTS