CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001719
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome c, testis-specific 
Protein Synonyms/Alias
  
Gene Name
 Cyct 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
9GDAEAGKKIFVQKCAacetylation[1]
Reference
 [1] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647
Functional Description
 Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. 
Sequence Annotation
 METAL 19 19 Iron (heme axial ligand).
 METAL 81 81 Iron (heme axial ligand).
 BINDING 15 15 Heme (covalent).
 BINDING 18 18 Heme (covalent).
 MOD_RES 2 2 N-acetylglycine.  
Keyword
 3D-structure; Acetylation; Apoptosis; Complete proteome; Direct protein sequencing; Electron transport; Heme; Iron; Metal-binding; Mitochondrion; Phosphoprotein; Reference proteome; Respiratory chain; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 105 AA 
Protein Sequence
MGDAEAGKKI FVQKCAQCHT VEKGGKHKTG PNLWGLFGRK TGQAPGFSYT DANKNKGVIW 60
SEETLMEYLE NPKKYIPGTK MIFAGIKKKS EREDLIKYLK QATSS 105 
Gene Ontology
 GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IDA:MGI.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IDA:MGI.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0042743; P:hydrogen peroxide metabolic process; IDA:MGI. 
Interpro
 IPR002327; Cyt_c_1A/1B.
 IPR009056; Cyt_c_dom.
 IPR003088; Cyt_c_I. 
Pfam
 PF00034; Cytochrom_C 
SMART
  
PROSITE
 PS51007; CYTC 
PRINTS
 PR00604; CYTCHRMECIAB.