CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017040
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger and SCAN domain-containing protein 29 
Protein Synonyms/Alias
 Zinc finger protein 690 
Gene Name
 ZSCAN29 
Gene Synonyms/Alias
 ZNF690 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
169MNPKEKLKPFQRSGLubiquitination[1]
180RSGLPFPKSGVVSRLacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 18 100 SCAN box.
 ZN_FING 678 700 C2H2-type 1.
 ZN_FING 706 728 C2H2-type 2.
 ZN_FING 734 756 C2H2-type 3.
 ZN_FING 762 784 C2H2-type 4.
 ZN_FING 790 812 C2H2-type 5.
 ZN_FING 818 840 C2H2-type 6.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 852 AA 
Protein Sequence
MMAKSALREN GTNSETFRQR FRRFHYQEVA GPREAFSQLW ELCCRWLRPE VRTKEQIVEL 60
LVLEQFLTVL PGEIQNWVQE QCPENGEEAV TLVEDLEREP GRPRSSVTVS VKGQEVRLEK 120
MTPPKSSQEL LSVRQESVEP QPRGVPKKER ARSPDLGPQE QMNPKEKLKP FQRSGLPFPK 180
SGVVSRLEQG EPWIPDLLGS KEKELPSGSH IGDRRVHADL LPSKKDRRSW VEQDHWSFED 240
EKVAGVHWGY EETRTLLAIL SQTEFYEALR NCHRNSQVYG AVAERLREYG FLRTLEQCRT 300
KFKGLQKSYR KVKSGHPPET CPFFEEMEAL MSAQVIALPS NGLEAAASHS GLVGSDAETE 360
EPGQRGWQHE EGAEEAVAQE SDSDDMDLEA TPQDPNSAAP VVFRSPGGVH WGYEETKTYL 420
AILSETQFYE ALRNCHRNSQ LYGAVAERLW EYGFLRTPEQ CRTKFKSLQT SYRKVKNGQA 480
PETCPFFEEM DALVSVRVAA PPNDGQEETA SCPVQGTSEA EAQKQAEEAD EATEEDSDDD 540
EEDTEIPPGA VITRAPVLFQ SPRGFEAGFE NEDNSKRDIS EEVQLHRTLL ARSERKIPRY 600
LHQGKGNESD CRSGRQWAKT SGEKRGKLTL PEKSLSEVLS QQRPCLGERP YKYLKYSKSF 660
GPNSLLMHQV SHQVENPYKC ADCGKSFSRS ARLIRHRRIH TGEKPYKCLD CGKSFRDSSN 720
FITHRRIHTG EKPYQCGECG KCFNQSSSLI IHQRTHTGEK PYQCEECGKS FNNSSHFSAH 780
RRIHTGERPH VCPDCGKSFS KSSDLRAHHR THTGEKPYGC HDCGKCFSKS SALNKHGEIH 840
AREKLLTQSA PK 852 
Gene Ontology
 GO:0005634; C:nucleus; IBA:RefGenome.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0016032; P:viral reproduction; IEA:InterPro. 
Interpro
 IPR008916; Retrov_capsid_C.
 IPR003309; Tscrpt_reg_SCAN.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF02023; SCAN 
SMART
 SM00431; SCAN
 SM00355; ZnF_C2H2 
PROSITE
 PS50804; SCAN_BOX
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS