CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019458
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 PCMTD1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
171YCGAGVQKDHENYMKubiquitination[1]
178KDHENYMKILLKVGGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 ACT_SITE 64 64 By similarity.
 LIPID 2 2 N-myristoyl glycine (Potential).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Lipoprotein; Myristate; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 357 AA 
Protein Sequence
MGGAVSAGED NDDLIDNLKE AQYIRTERVE QAFRAIDRGD YYLEGYRDNA YKDLAWKHGN 60
IHLSAPCIYS EVMEALKLQP GLSFLNLGSG TGYLSTMVGL ILGPFGINHG IELHSDVVEY 120
AKEKLESFIK NSDSFDKFEF CEPAFVVGNC LQIASDSHQY DRIYCGAGVQ KDHENYMKIL 180
LKVGGILVMP IEDQLTQIMR TGQNTWESKN ILAVSFAPLV QPSKNDNGKP DSVGLPPCAV 240
RNLQDLARIY IRRTLRNFIN DEMQAKGIPQ RAPPKRKRKR VKQRINTYVF VGNQLIPQPL 300
DSEEDEKMEE DNKEEEEKDH NEAMKPEEPP QNLLREKIMK LPLPESLKAY LTYFRDK 357 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro. 
Interpro
 IPR000682; PCMT. 
Pfam
 PF01135; PCMT 
SMART
  
PROSITE
 PS01279; PCMT 
PRINTS