CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013774
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tripartite motif-containing protein 58 
Protein Synonyms/Alias
  
Gene Name
 Trim58 
Gene Synonyms/Alias
 Gm16 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
165TQEANVGKKTIIWKEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 271 466 B30.2/SPRY.
 ZN_FING 15 59 RING-type.
 ZN_FING 90 131 B box-type.  
Keyword
 Coiled coil; Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 485 AA 
Protein Sequence
MATAPGERLQ EEARCSVCLD FLQEPISVDC GHSFCLRCIS EFCEKSDSAQ GVYACPQCRG 60
PFRPASFRPN RQLASLVDSV RQLGLGTGHA GSRQCARHGE DLSHFCEEDQ TMLCWVCDTS 120
PEHRSHRTET LQEAASRYQR MLRASLELVK KEMEEALTQE ANVGKKTIIW KEKVEMQRQR 180
FRLEFEKHRG FLAQEEQLQL RRLEEEERAT LQRLRDSRNR LAQQNKALKE LAEELEERSQ 240
RPAPGLLEGA RGVLTRCEAI TRLEPEAVPM DLKTVCRIPG MREMLRKFQV DVKLDPATAH 300
PSLLLTADLR SVQDAEVWRD VPSNPERFDT WPCILGLQGF SSGRHYWEVI VGERAEWGLG 360
VCRDSVLRKG ETTPSPENGV WAMWLLRGNE YMVLSSPSVP VLQDERPRRI GIFLDYEAGE 420
ISFYNVTNGS YIYTFNHLFS GVLRPYFFVC DTTPLILPPM TEAAPGNWTP RGIFDLAAAA 480
RNEEY 485 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR006574; PRY.
 IPR018355; SPla/RYanodine_receptor_subgr.
 IPR003877; SPRY_rcpt.
 IPR000315; Znf_B-box.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00622; SPRY
 PF00643; zf-B_box 
SMART
 SM00336; BBOX
 SM00589; PRY
 SM00184; RING
 SM00449; SPRY 
PROSITE
 PS50188; B302_SPRY
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS
 PR01407; BUTYPHLNCDUF.