CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036528
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 T-cell factor-4 variant X2 
Protein Synonyms/Alias
 Transcription factor 7-like 2 
Gene Name
 TCF7L2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51VGSLHSSKHQDSKKEubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 335 AA 
Protein Sequence
MSSFLSSRFP PHMVPPHHTL HTTGIPHPAI VTPTVKQESS QSDVGSLHSS KHQDSKKEEE 60
KKKPHIKKPL NAFMLYMKEM RAKVVAECTL KESAAINQIL GRRWHALSRE EQAKYYELAR 120
KERQLHMQLY PGWSARDNYG KKKKRKRDKQ PGETNEHSEC FLNPCLSLPP ITDLSAPKKC 180
RARFGLDQQN NWCGPCRRKK KCVRYIQGEG SCLSPPSSDG SLLDSPPPSP NLLGSPPRDA 240
KSQTEQTQPL SLSLKPDPLA HLSMMPPPPA LLLAEATHKA SALCPNGALD LPPAALQPAA 300
PSSSIAQPST SSLHSHSSLA GTQPQPLSLV TKSLE 335 
Gene Ontology
 GO:0016055; P:Wnt receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR009071; HMG_box_dom.
 IPR024940; TCF/LEF. 
Pfam
 PF00505; HMG_box 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS