| Tag | Content |
|---|
| CPLM ID | CPLM-011202 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proline dehydrogenase 1, mitochondrial |
Protein Synonyms/Alias | Proline oxidase; Protein sluggish-A |
Gene Name | slgA |
Gene Synonyms/Alias | slg; CG1417 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 354 | KTIKDLEKYYATLGD | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Converts proline to delta-1-pyrroline-5-carboxylate. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Proline metabolism; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 681 AA |
Protein Sequence | MALLRSLSAQ RTAISLVYGR NSSKSSNSVA VAACRSFHQR GSGSTSIAGE GAASESTRGV 60
NGARFLHSGD RPLQASTLVQ PEVVSSETVK RSMKQESSQE KNPSPAGSPQ RDPLDVSFND 120
PIAAFKSKTT GELIRAYLVY MICSSEKLVE HNMTLMKLAR NLLGQKLFVL LMKSSFYGHF 180
VAGENRHTIV PALERLRSFG VKPILDYSVE EDITQEEAEK REVESSVSSA GDKKEEGSMP 240
QYHVDKSFAD RRYKVSSART YFYLNEATCE RNMEIFIKCL EAVSDDDRKA PRAVATGATF 300
GTGITAIKLT ALGRPQLLLQ LSEVIMRTRK YMEDMVGGQG NVLTHHKTIK DLEKYYATLG 360
DNKDVKEFLN NVTSDKEGIL HLFPWSGIVD EDSQLSDTFR VPDPQTGQMR RLISQIPPKE 420
EEMFRNMIRR LNTIVKAAAD LDVRIMVDAE QTYFQPAISR ITLEMMRKYN KDKAIVFNTY 480
QCYLRETFRE VNTDLEQAKR QNFYFGAKLV RGAYMDQERD RAKSLGYPDP VNPTFEATTD 540
MYHRTLSECL RRIKLMKDCD DDARKIGIMV ASHNEDTVRF AIQQMKEIGI SPEDKVICFG 600
QLLGMCDYIT FPLGQAGYSA YKYIPYGPVE EVLPYLSRRA QENKGVLKKI KKEKRLLLSE 660
IRRRLMRGQL FYKPKGNYVP I 681 |
Gene Ontology | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:FlyBase. GO:0071949; F:FAD binding; ISS:UniProtKB. GO:0004657; F:proline dehydrogenase activity; IMP:FlyBase. GO:0006537; P:glutamate biosynthetic process; IEA:InterPro. GO:0007626; P:locomotory behavior; IMP:FlyBase. GO:0042331; P:phototaxis; IMP:FlyBase. GO:0006562; P:proline catabolic process; IMP:FlyBase. GO:0010133; P:proline catabolic process to glutamate; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |