CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033223
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcriptional activator GLI3 
Protein Synonyms/Alias
  
Gene Name
 GLI3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32TRTDVSEKAVASSTTacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 180 AA 
Protein Sequence
MEAQSHSSTT TEKKKVENSI VKCSTRTDVS EKAVASSTTS NEDESPGQTY HRERRNAITM 60
QPQNVQGLSK VSEEPSTSSD ERASLIKKEI HGSLPHVAEP SVPYRGTVFA MDPRNGYMEP 120
HYHPPHLFPA FHPPVPIDAR HHEGRYHYDP SPIPPLHMTS ALSSSPTYPD LPFIRISPHR 180 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0017053; C:transcriptional repressor complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0060873; P:anterior semicircular canal development; IEA:Compara.
 GO:0009952; P:anterior/posterior pattern specification; IEA:Compara.
 GO:0060840; P:artery development; IEA:Compara.
 GO:0007411; P:axon guidance; IEA:Compara.
 GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Compara.
 GO:0048593; P:camera-type eye morphogenesis; IEA:Compara.
 GO:0061005; P:cell differentiation involved in kidney development; IEA:Compara.
 GO:0021801; P:cerebral cortex radial glia guided migration; IEA:Compara.
 GO:0048589; P:developmental growth; IEA:Compara.
 GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Compara.
 GO:0042733; P:embryonic digit morphogenesis; IEA:Compara.
 GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Compara.
 GO:0021798; P:forebrain dorsal/ventral pattern formation; IEA:Compara.
 GO:0021861; P:forebrain radial glial cell differentiation; IEA:Compara.
 GO:0060364; P:frontal suture morphogenesis; IEA:Compara.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0007442; P:hindgut morphogenesis; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0060366; P:lambdoid suture morphogenesis; IEA:Compara.
 GO:0022018; P:lateral ganglionic eminence cell proliferation; IEA:Compara.
 GO:0060875; P:lateral semicircular canal development; IEA:Compara.
 GO:0030324; P:lung development; IEA:Compara.
 GO:0060594; P:mammary gland specification; IEA:Compara.
 GO:0030318; P:melanocyte differentiation; IEA:Compara.
 GO:0001656; P:metanephros development; IEA:Compara.
 GO:0046639; P:negative regulation of alpha-beta T cell differentiation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0045665; P:negative regulation of neuron differentiation; IEA:Compara.
 GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0045060; P:negative thymic T cell selection; IEA:Compara.
 GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Compara.
 GO:0048709; P:oligodendrocyte differentiation; IEA:Compara.
 GO:0021631; P:optic nerve morphogenesis; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IEA:Compara.
 GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Compara.
 GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Compara.
 GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Compara.
 GO:0042307; P:positive regulation of protein import into nucleus; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0016485; P:protein processing; IEA:Compara.
 GO:0009954; P:proximal/distal pattern formation; IEA:Compara.
 GO:0060367; P:sagittal suture morphogenesis; IEA:Compara.
 GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Compara.
 GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IEA:Compara.
 GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IEA:Compara.
 GO:0070242; P:thymocyte apoptotic process; IEA:Compara.
 GO:0043586; P:tongue development; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS