| Tag | Content |
|---|
| CPLM ID | CPLM-012977 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RNA polymerase II-associated protein 1 |
Protein Synonyms/Alias | |
Gene Name | Rpap1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 213 | RPNLITGKGLRSQAA | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. Required for interaction of the RNA polymerase II complex with acetylated histone H3 (By similarity). |
Sequence Annotation | MOD_RES 329 329 Phosphothreonine (By similarity).
MOD_RES 1123 1123 Phosphothreonine (By similarity). |
Keyword | Complete proteome; DNA-binding; DNA-directed RNA polymerase; Nucleotidyltransferase; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1400 AA |
Protein Sequence | MMLSRPKPGE SEVDLLRFQS QFLEAGAAPA VQLVKGSRRR GDAHPDQLPP QDHRDVVMLD 60
SLPDLPPALL PAPSKRARPS PGRPLPHDED PEERLNRHDE HITAVLSKIV ERDTSSVTVT 120
LPVPSGVAFP PVFHRSQERQ VKPAASSKRS IFAQEIAARR VSDNRAPSAE QVVPSPDAPE 180
GAVPCETPSS KDRGSQLPGR SHSFHRPNLI TGKGLRSQAA VQEVQTIHEE NVARLQAMDP 240
EEILKEQQQL LAQLDPSLVA FLRAHNHTRE QTETKATKEQ NPERPSVPVS KEEPIMSTCT 300
GESGTRDKLE DKLEDKLQPR TPALKLPMTP NKEWLHMDTV ELEKLHWTQD LPPLRRQQTQ 360
ERMQARFSLQ GELLEPDVDL PTHLGLHHHG EEAERAGYSL QELFHLTRSQ VSQQRALALH 420
VLSHIVGRAQ AGEFGDRLVG SVLRLLLDAG FLFLLRFSLD DRIDSVIAAA VRALRALLVA 480
PGDEELLDST FSWYHGASVF PMMPSHDDKE DEDEDEELTK EKVNRKTPEE GSRPPPDLAR 540
HDVIKGLLAT NLLPRFRYVL EVTCPGPSVV LDILAVLIRL ARHSLESAMR VLECPRLMET 600
IVREFLPTSW SPIGVGPAPS LYKVPCAAAM KLLRVLASAG RNIAARLLSS FDVRSRLCRF 660
IAEAPRDLAL PFEEAEILTT EAFRLWAVAA SYGQGGDLYR ELYPVLMRAL QTLPPELSTH 720
PLQPLSMQRM ASLLTLLTQL TLAASTQPEA TSGSVESCVV AIPSSITWTH VSGLKPLVEP 780
CLKQTLKFLR RPDVWNALGP VPSACLLFLG AYYQTWSQQS GLCPEDWLQD MERFLDEFLL 840
PLLSQPPLGR MWDSLRDCSP LCNPLSCAST PEALPSLVSL GCAGGCPPLS VAGSASPFPF 900
LTALLSLINT LGQIHKGLCR QLAVVLTAPG LQNYFLQCVA PAPAPQLTPF SAWALRHEYH 960
LQYLVLSLAQ KAATSQPEPA ASTALHHVMA LVLLSRLLPG SEFLAHELLL SCVFRLGFLP 1020
ENASGGPEAA DFSDGLSLGN SGDPHCRRGA LLVQACQDLP SIRSCYLAHC SPARASLLTS 1080
QALYRGELPR VSSLLLPVPK EPLLPTDWPF QPLIHLYHRA SDTPSGLPAA DTVGITMRVL 1140
QWVLVLESWR PEALWAVPPA ARLARLMCVY LVDSELFRET PIQRLVAALL ARLCQPQVLP 1200
NLKLDCPLPG LTSFPDLYAS FLDHFEAVSF GDHLFGALVL LPLQRRFSVT LRLALFGEHV 1260
GVLRALGLPL AQLPVPLECY TEPAEDSLAL LQLYFRALVT GALHARWCPV LYTVAVAHVN 1320
SFVFCQDPKS SDEVKAARRS MLQKVWLLAD KDLRQHLLHY KLPNSSLPEG FELYPQLPRL 1380
RQQYLQTLPT EVLQNGGFKT 1400 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW. GO:0032774; P:RNA biosynthetic process; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |