CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016254
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar fusion protein MON1 homolog A 
Protein Synonyms/Alias
  
Gene Name
 MON1A 
Gene Synonyms/Alias
 SAND1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
166FVLSEAGKPVYSRYGubiquitination[1]
453RHFLYKSKSSGLFTSubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Plays an important in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). 
Sequence Annotation
 MOD_RES 31 31 Phosphoserine.
 MOD_RES 56 56 Phosphoserine (By similarity).
 MOD_RES 57 57 Phosphotyrosine (By similarity).
 MOD_RES 69 69 Phosphoserine (By similarity).
 MOD_RES 72 72 Phosphoserine (By similarity).
 MOD_RES 91 91 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 555 AA 
Protein Sequence
MATDMQRKRS SECLDGTLTP SDGQSMERAE SPTPGMAQGM EPGAGQEGAM FVHARSYEDL 60
TESEDGAASG DSHKEGTRGP PPLPTDMRQI SQDFSELSTQ LTGVARDLQE EMLPGSSEDW 120
LEPPGAVGRP ATEPPREGTT EGDEEDATEA WRLHQKHVFV LSEAGKPVYS RYGSEEALSS 180
TMGVMVALVS FLEADKNAIR SIHADGYKVV FVRRSPLVLV AVARTRQSAQ ELAQELLYIY 240
YQILSLLTGA QLSHIFQQKQ NYDLRRLLSG SERITDNLLQ LMARDPSFLM GAARCLPLAA 300
AVRDTVSASL QQARARSLVF SILLARNQLV ALVRRKDQFL HPIDLHLLFN LISSSSSFRE 360
GEAWTPVCLP KFNAAGFFHA HISYLEPDTD LCLLLVSTDR EDFFAVSDCR RRFQERLRKR 420
GAHLALREAL RTPYYSVAQV GIPDLRHFLY KSKSSGLFTS PEIEAPYTSE EEQERLLGLY 480
QYLHSRAHNA SRPLKTIYYT GPNENLLAWV TGAFELYMCY SPLGTKASAV SAIHKLMRWI 540
RKEEDRLFIL TPLTY 555 
Gene Ontology
 GO:0006879; P:cellular iron ion homeostasis; IEA:Compara.
 GO:0009306; P:protein secretion; IEA:Compara. 
Interpro
 IPR004353; Vacuolar_fusion_protein_MON1. 
Pfam
 PF03164; Mon1 
SMART
  
PROSITE
  
PRINTS
 PR01546; YEAST73DUF.