CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032852
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chaperone, putative 
Protein Synonyms/Alias
  
Gene Name
 PFF0430w 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
171LPICLADKLADDLVEacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 543 AA 
Protein Sequence
MSIHLLNKKA DSLRSTNVLM TNMNASKGMY EIIKSNLGPK GSYKMLVSSS GAIKITKDGN 60
VLLNEMMIQH PTASMLSRIC SSIDETLGDG SSSNLIVATS LIYLSEKYIL YENIHPRIIT 120
QGFDIAKGIL LEFLDSMKIP VNIEENFDKE LLYNVCKTCI RTKLPICLAD KLADDLVESI 180
KIIYKPTKQI DLHMIEIMDI KRNMSINTKL VRGMVLDHGC RHPNMPNKLT KCFILVLNVS 240
LEYEKSEVFS SFVYSNAEDR DKLVESERKF TDDKVKKIIE LKKILVEKKF KETNEIYNFA 300
VFNQKGIDPI SLDLLAKENI MALRRIKRRN LERIVLCCGG NPCNNVYDLT EEDVGYAGLV 360
YEISINDEKY TFIEEVQNPK SCTIFIQAPN DYTIKQIKDA IRDGLRSIKN VIDDKCVLSG 420
AGSFEIMAYC KLKDEEKKIK GKQKFALDIY ANSLLNIPKV LLENSGLDIH QTLFNVIDKY 480
NEDRSEPLGL DLDTGEPIIA HLKGIYDNYC VKKEILSIAT AISQQILLVD EIIRAGKSMG 540
EEK 543 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012722; Chap_CCT_zeta.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2 
PRINTS
 PR00304; TCOMPLEXTCP1.