CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022596
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dynactin subunit 4 
Protein Synonyms/Alias
 Dynactin subunit p62 
Gene Name
 Dctn4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
18LYLVQGEKKVRAPLSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 414 414 Phosphothreonine.  
Keyword
 Acetylation; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 467 AA 
Protein Sequence
MASLLQSERV LYLVQGEKKV RAPLSQLYFC RYCSELRSLE CVSHEVDSHY CPSCLENMPS 60
AEAKLKKNRC ANCFDCPGCM HTLSTRATSI STQLPDDPAK TTMKKAYYLA CGFCRWTSRD 120
VGMADKSVAS GGWQEPENPH AQRMNKLIEY YQQLAQKEKV ERDRKKLARR RNYMPLAFSQ 180
HTIHVVDKYS LGTRLQRPRA GASISTLAGL SLREGEDQKE VKIEPAQAVA EVEPLPEDYY 240
TRPVNLTEVT TLQQRLLQPD LQPVSASQLY PRHKHLLIKR SLRCRKCEHN LSKPEFNPTS 300
IKFKIQLVAV NYIPEVRIMS IPNLRYMKES QVLLTLTNPV ENLTHVTLLE CEEGDPDNIN 360
STAKVVVPPK ELILAGKDAA AEYDELAEPQ DFQDDPDIVA FRKANKVGIF IKVTPQREEG 420
DVTVCFKMKH DFKNLAAPIR PMEESDQGTE VIWLTQHVEL SFGPLLP 467 
Gene Ontology
 GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005868; C:cytoplasmic dynein complex; TAS:RGD. 
Interpro
 IPR008603; Dynactin_p62. 
Pfam
 PF05502; Dynactin_p62 
SMART
  
PROSITE
  
PRINTS