CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030114
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcription factor SOX-5 
Protein Synonyms/Alias
  
Gene Name
 Sox5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
112ADVVDTLKQRKMEELubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 679 AA 
Protein Sequence
MLTDPDLPQE FERMSSKRPA SPYGETDGEV AMVTSRQKVE EEESERLPAF HLPLHEVDGN 60
KVMSSLAPYN SSTSPQKAEE GGRQSGESVS SAALGTPERR KGSLADVVDT LKQRKMEELI 120
KNEPEDTPSI EKLLSKDWKD KLLAMGSGNF GEIKGTPESL AEKERQLMGM INQLTSLREQ 180
LLAAHDEQKK LAASQIEKQR QQMELAKQQQ EQIARQQQQL LQQQHKINLL QQQIQVQGQL 240
PPLMIPVFPP DQRTLAAAAQ QGFLLPPGFS YKAGCSDPYP VQLIPTTMAA AAAATPGLGP 300
LQLQDEVAQP LNLSAKPKTS DGKSPASPTS PHMPALRINS GAGPLKASVP AALASPSARV 360
STIGYLNDHD AVTKAIQEAR QMKEQLRREQ QALDGKVAVV NSIGLSNCRT EKEKTTLESL 420
TQQLAVKQNE EGKFSHGMMD FNMSGDSDGS AGVSESRIYR ESRGRGSNEP HIKRPMNAFM 480
VWAKDERRKI LQAFPDMHNS NISKILGSRW KAMTNLEKQP YYEEQARLSK QHLEKYPDYK 540
YKPRPKRTCL VDGKKLRIGE YKAIMRNRRQ EMRQYFNVGQ QAQIPIATAG VVYPSAIAMA 600
GMPSPHLPSE HSSVSSSPEP GMPVIQSTYG AKGEEPHIKE EIQAEDINGE IYEEYDEEEE 660
DPDVDYGSDS ENHIAGQAN 679 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
 GO:0051216; P:cartilage development; IGI:MGI.
 GO:0045165; P:cell fate commitment; IGI:MGI.
 GO:0021953; P:central nervous system neuron differentiation; IGI:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0060164; P:regulation of timing of neuron differentiation; IMP:MGI. 
Interpro
 IPR009071; HMG_box_dom. 
Pfam
 PF00505; HMG_box 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS