UniProt Accession

 HINT3_PONAB; Q5R9L4 

Genbank Protein ID

 CR859092; CR859373 

Genbank Nucleotide ID

 CAH91284.1; CAH91546.1 

Protein Name

 Histidine triad nucleotide-binding protein 3 

Protein Synonyms/Alias

  

Gene Name

 HINT3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 

NCBI Taxa ID

 9601 

Lysine Modification

Position	Peptide	Type	References
179	TADHLIEKLRT****	ubiquitination	[1]

Reference

 [1] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048] 

Functional Description

 Hydrolyzes phosphoramidate and acyl-adenylate substrates. 

Sequence Annotation

 DOMAIN 49 160 HIT.
 NP_BIND 76 77 Purine nucleotide phosphoramidate (By
 NP_BIND 145 147 Purine nucleotide phosphoramidate (By
 MOTIF 143 147 Histidine triad motif.
 ACT_SITE 145 145 Tele-AMP-histidine intermediate (By
 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR001310; Histidine_triad_HIT.
 IPR011146; HIT-like. 

Pfam

  

SMART

  

PROSITE

 PS00892; HIT_1
 PS51084; HIT_2 

PRINTS