CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027771
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ppm1b protein 
Protein Synonyms/Alias
 Protein phosphatase 1B; Protein phosphatase 1B2 53 kDa isoform 
Gene Name
 Ppm1b 
Gene Synonyms/Alias
 ppm1b2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
90EDFRAADKSGSALEPubiquitination[1]
112GIRTGFLKIDEYMRNubiquitination[1]
314KRDSELDKHLESRVEubiquitination[1]
326RVEEIMQKSGEEGMPubiquitination[1]
391EEGGSQGKLVEALRQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 477 AA 
Protein Sequence
MGAFLDKPKT EKHNAHGAGN GLRYGLSSMQ GWRVEMEDAH TAVVGIPHGL DNWSFFAVYD 60
GHAGSRVANY CSTHLLEHIT TNEDFRAADK SGSALEPSVE SVKTGIRTGF LKIDEYMRNF 120
SDLRNGMDRS GSTAVGVMVS PTHMYFINCG DSRAVLCRNG QVCFSTQDHK PCNPVEKERI 180
QNAGGSVMIQ RVNGSLAVSR ALGDYDYKCV DGKGPTEQLV SPEPEVYEIV RAEEDEFVVL 240
ACDGIWDVMS NEELCEFVKS RLEVSDDLEN VCNWVVDTCL HKGSRDNMSV VLVCFSNAPK 300
VSEEAVKRDS ELDKHLESRV EEIMQKSGEE GMPDLAHVMR ILSAENIPNL PPGGGLAGKR 360
HVIEAVYSRL NPHKDNDGAS DEAEEGGSQG KLVEALRQMR VNHRGNYRQL LEEMLTSYRL 420
AKVEGEESPA DPAAAAASSN SDGGNPVAMQ ERDTEGGPAG LDSRNEDAGT KRSAENI 477 
Gene Ontology
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0030145; F:manganese ion binding; IEA:InterPro.
 GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
 GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:Compara. 
Interpro
 IPR001932; PP2C-like.
 IPR012911; PP2C_C.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
 PF00481; PP2C
 PF07830; PP2C_C 
SMART
 SM00331; PP2C_SIG
 SM00332; PP2Cc 
PROSITE
 PS01032; PP2C 
PRINTS