CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034444
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sorbin and SH3 domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Sorbs1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
431YSFSDDTKSPLSVPRubiquitination[1]
440PLSVPRSKSEMNYIEubiquitination[1]
523SPEEIDLKNEPWYKFubiquitination[1]
660LQGLSGLKRPSSSASubiquitination[1]
759ELLPPAEKAQPRKLAubiquitination[1]
764AEKAQPRKLAPVQVLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 938 AA 
Protein Sequence
MSSECDVGSS KAVVNGLASG NHGPDKDMDP TKICTGKGTV TLRASSSYRG TPSSSPVSPQ 60
ESPKHESKSD EWKLSSSADT NGNAQPSPLA AKGYRSVHPS LSADKPQGAT SSSSAPSEVI 120
VVPLYLVNTD RGQGQEGTAR TPASLGPLGC VHTVPATTPA ASPLTFPTLD DFIPPHLQRR 180
PHHSQPASAC GSLSPASQTS PPSPPPPLVP PVPEDLHRGL EPDLPGAVSS TGSPLLNEVS 240
SSHIETDSQD FPPTSRPSSA YPSTTIVNPT IVLLQHNREQ QKRLSSLSDP ASERRAGEQD 300
PVPTPAELTS PGRASERRAK DASRRVVRST QDLSDVSTDE VGIPLRNTER SKDWYKTMFK 360
QIHKLNRDTP EENPYFPTYK FPELPEILQN SEEDSSYTPT YQFPASTPSP KSEDDDSDVH 420
SPRYSFSDDT KSPLSVPRSK SEMNYIEGEK VVKRSATLPL PARSSSLKSS PERNDWEPPD 480
KKVDTRKYRA EPKSIYEYQP GKSSVLTNEK MSRDISPEEI DLKNEPWYKF FSELEFGRPP 540
PKKIWDYTPG DCSILPREDR KTNLEKDLSF CQAELEADLE KVETVNKSPS ANSPQSSAVS 600
PTPDITSEPP GYIYSSNFHA VKRESDGTPG GLASLENERQ IYKSVLEGGD IPLQGLSGLK 660
RPSSSASTKD SESPRHFIPA DYLESTEEFI RRRHDDKEMR PARAKFDFKA QTLKELPLQK 720
GDVVYIYRQI DQNWYEGEHH GRVGIFPRTY IELLPPAEKA QPRKLAPVQV LEYGEAIAKF 780
NFNGDTQVEM SFRKGERITL LRQVDENWYE GRIPGTSRQG IFPITYVDVL KRPLVKTPVD 840
YIDLPYSSSP SRSATVSPQQ PQAQQRRVTP DRSQPSLDLC SYQALYSYVP QNDDELELRD 900
GDIVDVMEKC DDGWFVGTSR RTRQFGTFPG NYVKPLYL 938 
Gene Ontology
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0005899; C:insulin receptor complex; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0001725; C:stress fiber; IDA:MGI.
 GO:0019901; F:protein kinase binding; IDA:MGI. 
Interpro
 IPR000108; p67phox.
 IPR011511; SH3_2.
 IPR001452; SH3_domain.
 IPR003127; Sorb. 
Pfam
 PF00018; SH3_1
 PF07653; SH3_2
 PF02208; Sorb 
SMART
 SM00326; SH3
 SM00459; Sorb 
PROSITE
 PS50002; SH3
 PS50831; SOHO 
PRINTS
 PR00499; P67PHOX.
 PR00452; SH3DOMAIN.