CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030305
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CLASP2 protein 
Protein Synonyms/Alias
  
Gene Name
 CLASP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
892SSNWSERKEGLLGLQubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1515 AA 
Protein Sequence
MEPRSMEYFC AQVQQKDVGG RLQVGQELLL YLGAPGAISD LEEDLGRLGK TVDALTGWVG 60
SSNYRVSLMG LEILSAFVDR LSTRFKSYVA MVIVALIDRM GDAKDKVRDE AQTLILKLMD 120
QVAPPMYIWE QLASGFKHKN FRSREGVCLC LIETLNIFGA QPLVISKLIP HLCILFGDSN 180
SQVRDAAILA IVEIYRHVGE KVRMDLYKRG IPPARLEMIF AKFDEVQSSG GMILSVCKDK 240
SFDDEESVDG NRPSSAASAF KVPAPKTSGN PANSARKPGS AGGPKVGAGA SKEGGAGAVD 300
EDDFIKAFTD VPSIQIYSSR ELEETLNKIR EILSDDKHDW DQRANALKKI RSLLVAGAAQ 360
YDCFFQHLRL LDGALKLSAK DLRSQVVREA CITVAHLSTV LGNKFDHGAE AIVPTLFNLV 420
PNSAKVMATS GCAAIRFIIR HTHVPRLIPL ITSNCTSKSV PVRRRSFEFL DLLLQEWQTH 480
SLERHAAVLV ETIKKGIHDA DAEARVEARK TYMGLRNHFP GEAETLYNSL EPSYQKSLQT 540
YLKSSGSVAS LPQSDRSSSS SQESLNRPFS SKWSTANPST VAGRVSAGSS KASSLPGSLQ 600
RSRSDIDVNA AAGAKAHHAA GQSVRSGRLG AGALNAGSYA SLEDTSDKLD GTASEDGRVR 660
AKLSAPLAGM GNAKADSRGR SRTKMVSQSQ PGSRSGSPGR VLTTTALSTV SSGVQRVLVN 720
SASAQKRSKI PRSQGCSREA SPSRLSVARS SRIPRPSVSQ GCSREASRES SRDTSPVRSF 780
QPLGPGYGIS QSSRLSSSVS AMRVLNTGSD VEEAVADALL LGDIRTKKKP ARRRYESYGM 840
HSDDDANSDA SSACSERSYS SRNGSIPTYM RQTEDVAEVL NRCASSNWSE RKEGLLGLQN 900
LLKNQRTLSR VELKRLCEIF TRMFADPHGK RVFSMFLETL VDFIQVHKDD LQDWLFVLLT 960
QLLKKMGADL LGSVQAKVQK ALDVTRESFP NDLQFNILMR FTVDQTQTPS LKVKVAILKY 1020
IETLAKQMDP GDFINSSETR LAVSRVITWT TEPKSSDVRK AAQSVLISLF ELNTPEFTML 1080
LGALPKTFQD GATKLLHNHL RNTGNGTQSS MGSPLTRPTP RSPANWSSPL TSPTNTSQNT 1140
LSPSAFDYDT ENMNSEDIYS SLRGVTEAIQ NFSFRSQEDM NEPLKRDSKK DDGDSMCGGP 1200
GMSDPRAGGD ATDSSQTALD NKASLLHSMP THSSPRSRDY NPYNYSDSIS PFNKSALKEA 1260
MFDDDADQFP DDLSLDHSDL VAELLKELSN HNERVEERKI ALYELMKLTQ EESFSVWDEH 1320
FKTILLLLLE TLGDKEPTIR ALALKVLREI LRHQPARFKN YAELTVMKTL EAHKDPHKEV 1380
VRSAEEAASV LATSISPEQC IKVLCPIIQT ADYPINLAAI KMQTKVIERV SKETLNLLLP 1440
EIMPGLIQGY DNSESSVRKA CVFCLVAVHA VIGDELKPHL SQLTGSKMKL LNLYIKRAQT 1500
GSGGADPTTD VSGQS 1515 
Gene Ontology
 GO:0005881; C:cytoplasmic microtubule; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0016477; P:cell migration; IEA:Compara.
 GO:0007163; P:establishment or maintenance of cell polarity; IEA:Compara.
 GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Compara. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR024395; CLASP_N_dom.
 IPR021133; HEAT_type_2. 
Pfam
 PF12348; CLASP_N 
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS