CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020740
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 39S ribosomal protein L45, mitochondrial 
Protein Synonyms/Alias
 L45mt; MRP-L45 
Gene Name
 Mrpl45 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
54EPKYKTEKEFLEYARacetylation[1]
62EFLEYARKAGLVIPQubiquitination[2]
133REFDANFKTKDFPEKacetylation[3]
133REFDANFKTKDFPEKsuccinylation[3]
135FDANFKTKDFPEKAKacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 306 AA 
Protein Sequence
MAAPVPRGLS SLYRTLGWWS RQPILVTQST TVVQVKTKSR FRPPTPEPKY KTEKEFLEYA 60
RKAGLVIPQE RLERPIHLAC TAGIFDPYVP PEGDARMSSL SKEGLTQRTE RLRKNAASQL 120
AIRKIREFDA NFKTKDFPEK AKDIFIEAHL CLNNSDHDRL HTLVTEHCFP DMVWDLKYKT 180
VRWGFVESLE PAQVVHVRCS GLVNQSNMYG QVTVRLHTRQ TLAIYDRFGR LMYGQEDVPK 240
DVLEYVVFER HLMNPYGSWR MHAKIVPAWA PPKQPILKTL MIPGPQLKPW EEYEETQGEA 300
QKPQLA 306 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW. 
Interpro
 IPR007379; Tim44-like_dom. 
Pfam
 PF04280; Tim44 
SMART
 SM00978; Tim44 
PROSITE
  
PRINTS