CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038749
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mediator of RNA polymerase II transcription subunit 23 
Protein Synonyms/Alias
  
Gene Name
 Med23 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
256ATLRFPLKGLLPYDKubiquitination[1]
263KGLLPYDKDLFEPQTubiquitination[1]
474LQQSLRNKSLQMNDYubiquitination[1]
682TRFLNDPKTVLSAESubiquitination[1]
1091LVDTMAGKSPGPFPNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1376 AA 
Protein Sequence
MVPMETQLQS IFEEVVKTEI IEEAFPGMFM DTPEDEKTKL ISCLAAFRQF WSGLSQESHE 60
QCVQWIVKFI HGQHSPKRIS FLYDCLAMAV ETGLLPPRMV CESLINSDSL EWERTQLWAL 120
TFKLVRKIIG GVDYKGVRDL LKAILEKILT IPNTVSSAVV QQLLAAREVI AYILERNACL 180
LPAYFAVTEI RKLYPEGKLP HWLLGNLVSD FVDTFRPTAR INSICGRCSL LPVVNNSGAI 240
CNSWKLDPAT LRFPLKGLLP YDKDLFEPQT ALLRYVLEQP YSRDMVCNML GLNKQTLNIA 300
QHKQRCPVLE DQLVDLVVYA MERSETEEKF DDGGTSQLLW QHLSSQLIFF VLFQFASFPH 360
MVLSLHQKLA GRGLIKGRDH LMWVLLQFIS GSIQKNALAD FLPVMKLFDL LYPEKECIPV 420
PDINKPQSTH AFAMTCIWIH LNRKAQNGDS TLQIPIPHSL KLHHEFLQQS LRNKSLQMND 480
YKIALLCNAY STNSECFTLP MGALVETIYG NGIMRVPLPG TSCLASASVT PLPMNLLDSL 540
TVHAKMSLIH SIATRVIKLA HTKSSVALAP ALVETYSRLL VYMEIESLGI KGFISQLLPT 600
VFKSHAWGIL HTLLEMFSHR MHHIQPHYRV QLLSHLHTLA AVAQTNQNQL HLCVESTALR 660
LITALGSSEV QPQFTRFLND PKTVLSAESE ELNRALILTL ARATHVTDFF TGSDSIQGTW 720
CKDILQTIMN FTPHNWASHT LSCFPAPLQA FFKQNNVPQE SRFNLKKNVE EEYRKWKSMT 780
DENEIITQFS VQGFPPLFLC LLWKMLLETD HISQIGYKVL ERIGARALVA HVRTFADFLV 840
YEFSTSAGGQ QLNKCIEILN DMVWKYNIVT LDRLILCLAM RSHEGNEAQV CYFIIQLLLL 900
KPNDFRNRVS DFVKENSPEH WLQSDWHTKH MSYHKKYPEK LYFEGLAEQV DPPVPIQSPY 960
LPIYFGNVCL RFLPVFDIVI HRFLELLPVS KSLETLLDHL GGLYKFHDRP VTYLYNTLHY 1020
YEMCLRNRDH LKRKLVHAII GSLKDNRPQG WCLSDTYLKH AMNAREDNPW VPEDSYYCKL 1080
IGRLVDTMAG KSPGPFPNCD WRFNEFPNPA AHALHVTCVE LMALAVPGKD VGNALLNVVL 1140
KSQPLVPREN ITAWMNAIGL IITALPEPYW IVLHDRIVNV ISSSSLTSET EWVGYPFRLF 1200
DFTACHQSYS EMSCSYTLAL AHAVWHHSSI GQLSLIPKFL TEALLPVVKT EFQLLYVYHL 1260
VGPFLQRFQQ ERTRCMIEIG VAFYDMLLNV DQCSTHLNYM DPICDFLYHM KYMFTGDSVK 1320
EQVEKIICNL KPALKLRLRF ITHISKMEPA VPPQALNSGS PAPQSNQVPA SLPVTQ 1376 
Gene Ontology
 GO:0016592; C:mediator complex; IDA:MGI.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:Compara. 
Interpro
 IPR021629; Mediator_Med23. 
Pfam
 PF11573; Med23 
SMART
  
PROSITE
  
PRINTS