UniProt Accession

 TVA3_HUMAN; P01737 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 T-cell receptor alpha chain V region PY14 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
77	TSAATLVKGINGFEA	ubiquitination	[1]
87	NGFEAEFKKSETSFH	ubiquitination	[1]
88	GFEAEFKKSETSFHL	ubiquitination	[1, 2]
97	ETSFHLTKPSAHMSD	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

 REGION 21 112 V segment.
 REGION 113 118 D segment.
 REGION 119 135 J segment.
 CARBOHYD 118 118 N-linked (GlcNAc...).  

Keyword

 Complete proteome; Glycoprotein; Immunoglobulin domain; Receptor; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 135 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; NAS:UniProtKB.
 GO:0042287; F:MHC protein binding; NAS:UniProtKB.
 GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
 GO:0006955; P:immune response; NAS:UniProtKB.
 GO:0031295; P:T cell costimulation; TAS:Reactome.
 GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set. 

Pfam

 PF07686; V-set 

SMART

 SM00409; IG 

PROSITE

 PS50835; IG_LIKE 

PRINTS