CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032494
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Eukaryotic translation initiation factor 3 subunit L 
Protein Synonyms/Alias
 eIF3l 
Gene Name
 TGGT1_112540, TGME49_073460, TGVEG_020700 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
413IKEKYSDKFYKLQQEacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 639 AA 
Protein Sequence
MSGEGQVADA GSLPVEKREE GAQVGHEEDD SLSPDSRFPV SPSNQASQNV EGEGLDDAAL 60
DRMMGEKVRF ENDVEEFLRS LYDEVYDRNV DAIRRLYEVE FPALTERYYA ERRWPSVDEV 120
GTFYRQFDRY HCLIITLYKE LYYRHLFLKC QQEITWEDRR LAWENYALLI NFLAEVECRP 180
DDQKDGKSLR LPLQWLWDIL DEFVYQFQEA CRWRQRIARR LPEDEEERAL FLKEMDKDCD 240
VWKASPVLEF LHALVQRSEV QDLLRQPKDD ATKNKLFESE IRFQLGYFAM ILLLRLHVLM 300
GDYFMGVKSV ESIELASRGF YWKVPAAHVT LFYHLGFAYT MMRRYTDAIR VMSQLLVFVS 360
RQRSYLSAHF YQQMAMNKAV DKMYILVMLC ASLCNVKLDE SVNQMIKEKY SDKFYKLQQE 420
NDETYCDLFT WACPKFINPA TPSFEDPQAL ERFANSYSEV QLRQCKMFFK EVEFHKKIST 480
INSFAKLYNN IQLSKLASLM ELSDKDPEDA VRSEILSVKY KGRQKVWRSG SLLSGDLTPS 540
SSDNSVEFYM DQDMIHVRSQ QSQKVYVDQF LKQIERSQHL FNSIQNSARS GQRDNRGQGE 600
RGGNQNSERE KFDRSQDRRN YGGHAGASEM PKREQAALA 639 
Gene Ontology
 GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP.
 GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP.
 GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:HAMAP.
 GO:0003743; F:translation initiation factor activity; IEA:HAMAP.
 GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP.
 GO:0006446; P:regulation of translational initiation; IEA:HAMAP. 
Interpro
 IPR019382; eIF3l. 
Pfam
 PF10255; Paf67 
SMART
  
PROSITE
  
PRINTS