UniProt Accession

 B1AT36_MOUSE; B1AT36 

Genbank Protein ID

 AL645687; AL683815 

Genbank Nucleotide ID

  

Protein Name

 26S proteasome non-ATPase regulatory subunit 12 

Protein Synonyms/Alias

  

Gene Name

 Psmd12 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
33	QRLPECEKLAKASDM	acetylation	[1]
133	TKTLATIKEQNGDVK	ubiquitination	[2]
192	ISKKINTKFFQEENT	ubiquitination	[2]
242	CIQAESDKWQQALKS	acetylation	[1]
274	VHRISSDKKLEEIPK	ubiquitination	[2]
310	DYGVELRKGSSETPA	ubiquitination	[2]
348	HNIRIMAKYYTRITM	acetylation	[1]
385	VNKTIFAKVDRLAGV	acetylation	[1]
428	KTTHLIAKEEMIHNL	acetylation	[1, 3]
428	KTTHLIAKEEMIHNL	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 436 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR000717; PCI_dom.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF01399; PCI 

SMART

 SM00088; PINT 

PROSITE

  

PRINTS