| Tag | Content |
|---|
| CPLM ID | CPLM-023069 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nocturnin |
Protein Synonyms/Alias | CCR4 protein homolog |
Gene Name | CCRN4L |
Gene Synonyms/Alias | CCR4; NOC |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 365 | EPPYTTWKIRTSGEC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Component of the circadian clock or downstream effector of clock function. Exhibits a high amplitude circadian rhythm with maximal levels in early evening. In constant darkness or constant light, the amplitude of the rhythm decreases (By similarity). |
Sequence Annotation | |
Keyword | Biological rhythms; Complete proteome; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 431 AA |
Protein Sequence | MFHSPRRLCS ALLQRDAPGL RRLPAPGLRR PLSPPAAVPR PASPRLLAAA SAASGAARSC 60
SRTVCSMGTG TSRLYSALAK TLNSSAASQH PEYLVSPDPE HLEPIDPKEL LEECRAVLHT 120
RPPRFQRDFV DLRTDCPSTH PPIRVMQWNI LAQALGEGKD NFVQCPVEAL KWEERKCLIL 180
EEILAYQPDI LCLQEVDHYF DTFQPLLSRL GYQGTFFPKP WSPCLDVEHN NGPDGCALFF 240
LQNRFKLVNS ANIRLTAMTL KTNQVAIAQT LECKESGRQF CIAVTHLKAR TGWERFRSAQ 300
GCDLLQNLQN ITQGAKIPLI VCGDFNAEPT EEVYKHFASS SLNLNSAYKL LSADGQSEPP 360
YTTWKIRTSG ECRHTLDYIW YSKHALNVRS ALDLLTEEQI GPNRLPSFNY PSDHLSLVCD 420
FSFTEESDGL S 431 |
Gene Ontology | GO:0000932; C:cytoplasmic mRNA processing body; IEA:Compara. GO:0005654; C:nucleoplasm; TAS:Reactome. GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. GO:0033962; P:cytoplasmic mRNA processing body assembly; IEA:Compara. GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:Compara. GO:0048511; P:rhythmic process; IEA:UniProtKB-KW. GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |