| Tag | Content |
|---|
| CPLM ID | CPLM-019930 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peroxisome assembly factor 2 |
Protein Synonyms/Alias | PAF-2; Peroxin-6; Peroxisomal biogenesis factor 6; Peroxisomal-type ATPase 1 |
Gene Name | Pex6 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 307 | GSIAPENKGSCSPLP | ubiquitination | [1] | | 511 | SSRAVETKLQATFSR | ubiquitination | [1] | | 715 | VGGLQDVKKEILETI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Probably required for protein import into peroxisomes. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (By similarity). |
Sequence Annotation | NP_BIND 471 478 ATP (Potential).
NP_BIND 745 752 ATP (Potential). |
Keyword | ATP-binding; Complete proteome; Cytoplasm; Membrane; Nucleotide-binding; Peroxisome; Peroxisome biogenesis; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 981 AA |
Protein Sequence | MALAVLRVLD PFPTETPPLA VLLPPGGPWP ATGLGLVLAL RPASESPAKP ALLVAAVEGS 60
GAQGEQRGPG PPPLLVSRAL LRVLALGPGA RVRARLVRRP PALGWALLAT APGPGLGPRV 120
GPLLVRRGET LPVPGSRVLE TRPALQGLLG PGTRLAVTEL RGRAKLGQES RDHSHPPPPP 180
VVSSFAASHS VRRLRGVLGG TGDALGVSRS CLRSLGLFQG EWVWVAQVAE LPNSSQPRLA 240
QVQVLEPRWE LSERLGPNSG QQPGEPLADG LVFLPATLAF NLGCDPLEVG ELRIQRYLEG 300
SIAPENKGSC SPLPGPPFAR ELHIEILSSP HYSANGNYDH VLYRHFQTPR VVQEGDVLCV 360
STAGQVEILE GSLERLPRWR EMFFKVKKTV GEAPEGPASA FLADTTHTSL YLAGTALSHV 420
PSLPSGRSPP WDSLSPPGLE ALVNELCAIL KPHLQPGGTL LTGTSCVLLQ GPPGSGKTTA 480
VTAACSRLGL HLLKVPCSSL CADSSRAVET KLQATFSRAR RCRPAVLLLT AVDLLGRDRD 540
GLGEDARVAA TLRHLLLDED ALSRCPPLMV VATTSRVQDL PTDVQTAFPH ELEVPVLSEA 600
QRLSILQALT AHLPLGQEVN LPQLARRCAG FVVGDLYALL THTCRAACTR IRASGSAGGL 660
SEEDEGDLCV AGFPLLAEDF GQALDQLQTA HSQAVGAPRI PSVSWHDVGG LQDVKKEILE 720
TIQLPLEHPE LLSLGLRRSG LLLHGPPGTG KTLLAKAVAT ECSLTFLSVK GPELINMYVG 780
QSEENVREVF ARARAAAPCI IFFDELDSLA PSRGRSGDSG GVMDRVVSQL LAELDGLHST 840
QDVFVIGATN RPDLLDPALL RPGRFDKLVF VGASEDRASQ LRVLSAITRK FKLEASVSLA 900
NVLDCCPPQL TGADLYSLCS DAMMTALKRR VRDLEEGLEL RSSALLLTME DLLQAAARLQ 960
PSVSEQELLR YKRIQRKFAA C 981 |
Gene Ontology | GO:0005829; C:cytosol; IEA:Compara. GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0042623; F:ATPase activity, coupled; IEA:Compara. GO:0016561; P:protein import into peroxisome matrix, translocation; IEA:Compara. GO:0050821; P:protein stabilization; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |