UniProt Accession

 HOLC_ECOLI; P28905; P11649; Q2M650 

Genbank Protein ID

 L04574; Z14155; U14003; U00096; AP009048; X15130 

Genbank Nucleotide ID

 AAA70368.1; CAA78524.1; AAA97156.1; AAC77216.1; BAE78256.1; CAA33226.1 

Protein Name

 DNA polymerase III subunit chi 

Protein Synonyms/Alias

  

Gene Name

 holC 

Gene Synonyms/Alias

 b4259; JW4216 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
47	LIACEDEKQAYRLDE	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 147 AA 

Protein Sequence

Gene Ontology

 GO:0043847; C:DNA polymerase III, clamp loader chi/psi subcomplex; IPI:EcoliWiki.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003887; F:DNA-directed DNA polymerase activity; IPI:EcoliWiki.
 GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
 GO:0032298; P:positive regulation of DNA-dependent DNA replication initiation; IDA:EcoliWiki. 

Interpro

 IPR007459; DNA_pol3_chi. 

Pfam

 PF04364; DNA_pol3_chi 

SMART

  

PROSITE

  

PRINTS