CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029084
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Abl interactor 1 
Protein Synonyms/Alias
  
Gene Name
 ABI1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
16EEEIPSGKRALIESYubiquitination[1]
43NYIQATDKRKALEETubiquitination[2]
123KNTSRTHKIIAPANMubiquitination[2]
139RPVRYIRKPIDYTVLubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 509 AA 
Protein Sequence
MAELQMLLEE EIPSGKRALI ESYQNLTRVA DYCENNYIQA TDKRKALEET KAYTTQSLAS 60
VAYQINALAN NVLQLLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR 120
THKIIAPANM ERPVRYIRKP IDYTVLDDVG HGVKKWHKII HGNNQPARTG TLSRTNPPTQ 180
KPPSPPMSGR GTLGRNTPYK TLEPVKPPTV PNDYMTSPAR LGSQHSPGRT ASLNQRPRTH 240
SGSSGGSGSR ENSGSSSIGI PIAVPTPSPP TIGPENISVP PPSGAPPAPP LAPLLPVSTV 300
IAAPGSAPGS QYGTMTRQIS RHNSTTSSTS SGGYRRTPSV TAQFSAQPHV NGGPLYSQNS 360
ISIAPPPPPM PQLTPQIPLT GFVARVQENI ADSPTPPPPP PPDDIPMFDD SPPPPPPPPV 420
DYEDEEAAVV QYNDPYADGD PAWAPKNYIE KVVAIYDYTK DKDDELSFME GAIIYVIKKN 480
DDGWYEGVCN RVTGLFPGNY VESIMHYTD 509 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro. 
Interpro
 IPR012849; Abl-interactor_HHR_dom.
 IPR000108; p67phox.
 IPR001452; SH3_domain.
 IPR000727; T_SNARE_dom. 
Pfam
 PF07815; Abi_HHR
 PF00018; SH3_1 
SMART
 SM00326; SH3 
PROSITE
 PS50002; SH3
 PS50192; T_SNARE 
PRINTS
 PR00499; P67PHOX.
 PR00452; SH3DOMAIN.