CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045580
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Tnc 
Protein Synonyms/Alias
  
Gene Name
 Tnc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1914RFSVGDAKSRYKLKVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2018 AA 
Protein Sequence
MGAVTWLLPG IFLALFALTP EGGVLKKVIR HKRESGLNLT LPEENQPVVF NHIYNIKLPM 60
GSQCSVDLES TSGEKDLSPT PESSGSFQEH TVDGENQIVF THRINIPRRA CGCAAAPDVK 120
ELLSRLEELE MLVSSLREQC TMGTGCCLQP AEGRLDSRPF CSGRGNFSAE GCGCVCEPGW 180
KGPNCSEPEC PGNCNLRGQC LDGQCICDQG FTGEDCSQLA CPNDCNDQGK CVNGVCVCFE 240
GYAGLDCGLE VCPVPCSEEH GMCVDGRCVC KDGFAGEDCN EPLCFNNCNN RGRCVENECV 300
CDEGFTGEDC SELICPNDCF DRGRCINGTC YCEEGFTGED CGELTCPNNC QGHGQCEEGQ 360
CVCNEGFAGA DCSEKRCPAD CHHHGRCLNG QCECDDGFTG ADCGELQCPN GCSGHGRCVN 420
GQCVCDEGYT GEDCSQRRCP NDCHNRGHCV QGKCICEQGF KGFDCSEMSC PNDCHQHGRC 480
VNGMCICDDD YTGEDCRDRR CPRDCSQRGR CVDGQCICED GFTGSDCAEL SCPGDCHGHG 540
RCVNGQCICH EGFTGKDCKE QRCPSDCHGQ GRCEDGQCIC HEGFTGLDCG QRSCPNDCSN 600
QGQCVAGRCI CNEGYTGVDC SEVSPPKDLI VTEVTEETVN LAWDNEMRVT EYLIMYTPTH 660
ADGLEMQFRV PGDQTSTTIR ELEPGVEYFI HVFAILENKR SIPVSARVAT YLPAPEGLKF 720
KSIKETSVEV EWDPLDIAFE TWEIIFRNMN KEDEGEITKS LRRPETSYRQ TGLAPGQEYE 780
ISLHIVKNNT RGPGLKKVTT TRLDAPSQIE VRDITDTTAL ITWSKPLAEI DSIELSYGIK 840
DVPGDRTTID LTHEDNQYSI GNLKPDTEYE VSLISRRVDM ASNPAKETFI TGLDAPRNLR 900
RVSQTDNSIT LEWRNVKADI DSYRIKYAPI SGGDHAEIDV PKSQQATTKT TLTGLRPGTE 960
YGVGVSAVKG DKEGDPATIN AATEIDAPRD LQVSETTQDS LTLFWKTPLA KFDRYRLNYS 1020
LPTGQSIEIQ LPKDATSHVL TDLEPGQEYT VLLTAEKGRH KSKPARVKAS TEEVPSLENL 1080
TVTEAGWDGL RLNWTADDLA YEYFVIQVQE ANKVETAHNF TVLGNLRTAD IPGLKAATPY 1140
RVSIYGVARG YKTPVLSAET FTGKTPSLGE VTVAEVGWDA LKLNWTAPEG AYTNFFIQVL 1200
EADMTQTVQN LTVPGGLRSV DLPGLKAATR YYITVRGVTQ DFSTAPLSVE VLTEEIPQLG 1260
GLSVTEVSWD SLTLNWTTDD LAYKHFIIQV QEANNVEAAQ NLTVSGSLRV VDIPGLKADT 1320
PYRVSIYGVI QGYRTPMLSA DVSTAKEPEI GNLNISDVTP ESFNLSWTAT DGIFDMFTIE 1380
IIDSNRLLQT AEHNISGAER TAHISGLPPS TDFIVYLSGI APSIRTKTIS TTATTEAEPE 1440
VDNLLVSDAT PDGFRLSWTA DEGIFDSFVI RIRDTKKQSE PQEITLPSPD RTRDITGLRE 1500
ATEYEIELYG ISRGRRSQPV SAIATTAMGS PKEIMFSDIT ENAATVSWRA PTAQVESFRI 1560
TYVPVTGGPP SMVTVDGTDT ETRLVRLTPG VEYHVSVIAM KGFEESDPVS GSLITALDGP 1620
SGLLTANITD SEALAMWQPA IATVDSYVIS YTGERVPEIT RTVSGNTVEF ELHDLEPATE 1680
YTLSVFAEKG HQKSSTIATK FTTDLDSPRE LTATEVQSET ALLTWRPPRA SVTGYLLVYE 1740
SVDGTVKEVI VGPDTTSYSL ADLSPSTHYT ARIQALSGSL RSKLIQTIFT TIGLLYPFPR 1800
DCSQAMLNGD TTSGLYTIYI NGDKTQALEV YCDMTSDGGG WIVFLRRKNG REDFYRNWKA 1860
YAAGFGDRRE EFWLGLDNLS KITAQGQYEL RVDLQDHGES AYAVYDRFSV GDAKSRYKLK 1920
VEGYSGTAAD ILGCHKERSF RKWDKDEKNG LXXCRLPHKE AIWYDGRERT RLPACFGDSA 1980
SQGVNWFHWK GHEYSIQFAE MKLRPSNFRN LEGRRKRA 2018 
Gene Ontology
 GO:0005578; C:proteinaceous extracellular matrix; IDA:RGD.
 GO:0060447; P:bud outgrowth involved in lung branching; IMP:RGD.
 GO:0071799; P:cellular response to prostaglandin D stimulus; IEP:RGD.
 GO:0071300; P:cellular response to retinoic acid; IEP:RGD.
 GO:0071305; P:cellular response to vitamin D; IEP:RGD.
 GO:0007162; P:negative regulation of cell adhesion; IDA:RGD.
 GO:0031175; P:neuron projection development; IMP:RGD.
 GO:0042475; P:odontogenesis of dentin-containing tooth; IEP:RGD.
 GO:0045471; P:response to ethanol; IEP:RGD.
 GO:0071774; P:response to fibroblast growth factor stimulus; IEP:RGD.
 GO:0009612; P:response to mechanical stimulus; IEP:RGD.
 GO:0042060; P:wound healing; IEP:RGD. 
Interpro
 IPR000742; EG-like_dom.
 IPR013032; EGF-like_CS.
 IPR013111; EGF_extracell.
 IPR014716; Fibrinogen_a/b/g_C_1.
 IPR002181; Fibrinogen_a/b/g_C_dom.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold. 
Pfam
 PF07974; EGF_2
 PF00147; Fibrinogen_C
 PF00041; fn3
 PF12661; hEGF 
SMART
 SM00181; EGF
 SM00186; FBG
 SM00060; FN3 
PROSITE
 PS00022; EGF_1
 PS01186; EGF_2
 PS50026; EGF_3
 PS51406; FIBRINOGEN_C_2
 PS50853; FN3 
PRINTS