CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010131
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Uncharacterized RNA pseudouridine synthase MG209 homolog 
Protein Synonyms/Alias
 RNA pseudouridylate synthase; RNA-uridine isomerase 
Gene Name
 MPN_292; H10_orf309, MP543 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
292LDKTFSDKLDNLNLKacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
  
Sequence Annotation
 DOMAIN 11 87 S4 RNA-binding.
 ACT_SITE 131 131 By similarity.  
Keyword
 Complete proteome; Isomerase; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
MEQTFSVTTA QRLDTFLATL LNLSRVKVAK LIVDGLVSVN GKKITKNGWL VQPEDRVHVN 60
WSEELFEKVP VEVQPYDFPL DILYEDEQIM VVNKPNGLIS HPTSFNESES LLGAALFHCN 120
HQPVFLVHRL DRDTSGVIML AKNQSSLLHL QKQLQQRVMK RYYLALVHFP LDSLSGTISA 180
PLERVGNNKV MWKVGNSSNK AKNAFTKFTV LNQNEKAALI KCELLTGRTH QIRVHLQFIK 240
HPVYNDPLYG LKSEQATEYG QYLHAQQISF IHPTLNKEMG FEAQLDKTFS DKLDNLNLKI 300
ANSLYALFQ 309 
Gene Ontology
 GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0001522; P:pseudouridine synthesis; IEA:InterPro. 
Interpro
 IPR020103; PsdUridine_synth_cat_dom.
 IPR006225; PsdUridine_synth_RluC/D.
 IPR006224; PsdUridine_synth_RluC/D_CS.
 IPR006145; PsdUridine_synth_RsuA/RluD.
 IPR002942; S4_RNA-bd. 
Pfam
 PF00849; PseudoU_synth_2
 PF01479; S4 
SMART
 SM00363; S4 
PROSITE
 PS01129; PSI_RLU
 PS50889; S4 
PRINTS