CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016931
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Superoxide dismutase [Fe] 
Protein Synonyms/Alias
 FeSOD 
Gene Name
 SODB 
Gene Synonyms/Alias
 PF08_0071 
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
38HHAGYVNKLNTLIKDacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209
Functional Description
 Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. 
Sequence Annotation
 METAL 27 27 Iron.
 METAL 74 74 Iron.
 METAL 158 158 Iron.
 METAL 162 162 Iron.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Iron; Metal-binding; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MVITLPKLKY ALNALSPHIS EETLNFHYNK HHAGYVNKLN TLIKDTPFAE KSLLDIVKES 60
SGAIFNNAAQ IWNHTFYWDS MGPDCGGEPH GEIKEKIQED FGSFNNFKEQ FSNILCGHFG 120
SGWGWLALNN NNKLVILQTH DAGNPIKDNT GIPILTCDIW EHAYYIDYRN DRASYVKAWW 180
NLVNWNFANE NLKKAMQK 198 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004784; F:superoxide dismutase activity; IEA:EC.
 GO:0006979; P:response to oxidative stress; ISS:GeneDB_Pfalciparum.
 GO:0006801; P:superoxide metabolic process; IEA:InterPro. 
Interpro
 IPR001189; Mn/Fe_SOD.
 IPR019833; Mn/Fe_SOD_BS.
 IPR019832; Mn/Fe_SOD_C.
 IPR019831; Mn/Fe_SOD_N. 
Pfam
 PF02777; Sod_Fe_C
 PF00081; Sod_Fe_N 
SMART
  
PROSITE
 PS00088; SOD_MN 
PRINTS
 PR01703; MNSODISMTASE.