UniProt Accession

 FSAB_ECOLI; P32669; Q2M8P2 

Genbank Protein ID

 U00006; U00096; AP009048 

Genbank Nucleotide ID

 AAC43052.1; AAC76928.1; BAE77364.1 

Protein Name

 Fructose-6-phosphate aldolase 2 

Protein Synonyms/Alias

 Fructose-6-phosphate aldolase B; FSAB 

Gene Name

 fsaB 

Gene Synonyms/Alias

 talC; yijG; b3946; JW3918 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
85	AIPGIVVKIPVTSEG	acetylation	[1]
168	MVLAASFKTPRQALD	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction. Can utilize hydroxyacetone as an alternative donor substrate. Is also able to catalyze the direct self-aldol addition of glycolaldehyde. Is less catalytically efficient than the isozyme FsaA. Does not display transaldolase activity. 

Sequence Annotation

 ACT_SITE 85 85 Schiff-base intermediate with substrate  

Keyword

 Carbohydrate metabolism; Complete proteome; Cytoplasm; Lyase; Reference proteome; Schiff base. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 220 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0097023; F:fructose 6-phosphate aldolase activity; IDA:EcoCyc.
 GO:0006000; P:fructose metabolic process; IEA:HAMAP. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR023001; F6P_aldolase.
 IPR001585; Transaldolase.
 IPR004731; Transaldolase_3A/3B.
 IPR018225; Transaldolase_AS. 

Pfam

 PF00923; Transaldolase 

SMART

  

PROSITE

 PS01054; TRANSALDOLASE_1
 PS00958; TRANSALDOLASE_2 

PRINTS